McInally T - Search Results

1

Relative binding affinities of integrin antagonists by equilibrium dialysis and liquid chromatography-mass spectrometry.

Tipping WJ, Tshuma N, Adams J, Haywood HT, Rowedder JE, Fray MJ, McInally T, Macdonald SJ, Oldham NJ. Tipping WJ, et al. Among authors: mcinally t. ACS Med Chem Lett. 2014 Dec 22;6(2):221-4. doi: 10.1021/ml500395v. eCollection 2015 Feb 12. ACS Med Chem Lett. 2014. PMID: 25699153 Free PMC article.

2

Structure Activity Relationships of αv Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents.

Adams J, Anderson EC, Blackham EE, Chiu YW, Clarke T, Eccles N, Gill LA, Haye JJ, Haywood HT, Hoenig CR, Kausas M, Le J, Russell HL, Smedley C, Tipping WJ, Tongue T, Wood CC, Yeung J, Rowedder JE, Fray MJ, McInally T, Macdonald SJ. Adams J, et al. Among authors: mcinally t. ACS Med Chem Lett. 2014 Sep 19;5(11):1207-12. doi: 10.1021/ml5002079. eCollection 2014 Nov 13. ACS Med Chem Lett. 2014. PMID: 25408832 Free PMC article.

3

Passing on the medicinal chemistry baton: training undergraduates to be industry-ready through research projects between the University of Nottingham and GlaxoSmithKline.

Macdonald SJ, Fray MJ, McInally T. Macdonald SJ, et al. Among authors: mcinally t. Drug Discov Today. 2016 Jun;21(6):880-7. doi: 10.1016/j.drudis.2016.01.015. Epub 2016 Feb 4. Drug Discov Today. 2016. PMID: 26852693 Review.

4

Unusual Undergraduate Training in Medicinal Chemistry in Collaboration between Academia and Industry.

McInally T, Macdonald SJF. McInally T, et al. J Med Chem. 2017 Oct 12;60(19):7958-7964. doi: 10.1021/acs.jmedchem.7b00198. Epub 2017 May 23. J Med Chem. 2017. PMID: 28535049 Review.

5

Late-Stage Functionalization by Chan-Lam Amination: Rapid Access to Potent and Selective Integrin Inhibitors.

Robinson H, Oatley SA, Rowedder JE, Slade P, Macdonald SJF, Argent SP, Hirst JD, McInally T, Moody CJ. Robinson H, et al. Among authors: mcinally t. Chemistry. 2020 Jun 18;26(34):7678-7684. doi: 10.1002/chem.202001059. Epub 2020 May 26. Chemistry. 2020. PMID: 32129907

6

Active Search for Computer-aided Drug Design.

Oglic D, Oatley SA, Macdonald SJF, Mcinally T, Garnett R, Hirst JD, Gärtner T. Oglic D, et al. Among authors: mcinally t. Mol Inform. 2018 Jan;37(1-2). doi: 10.1002/minf.201700130. Epub 2018 Feb 1. Mol Inform. 2018. PMID: 29388736

7

1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.

Tinker AC, Beaton HG, Boughton-Smith N, Cook TR, Cooper SL, Fraser-Rae L, Hallam K, Hamley P, McInally T, Nicholls DJ, Pimm AD, Wallace AV. Tinker AC, et al. Among authors: mcinally t. J Med Chem. 2003 Mar 13;46(6):913-6. doi: 10.1021/jm0255926. J Med Chem. 2003. PMID: 12620067

8

Hit-to-Lead studies: the discovery of potent adamantane amide P2X7 receptor antagonists.

Baxter A, Bent J, Bowers K, Braddock M, Brough S, Fagura M, Lawson M, McInally T, Mortimore M, Robertson M, Weaver R, Webborn P. Baxter A, et al. Among authors: mcinally t. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4047-50. doi: 10.1016/j.bmcl.2003.08.034. Bioorg Med Chem Lett. 2003. PMID: 14592505

9

Switching between agonists and antagonists at CRTh2 in a series of highly potent and selective biaryl phenoxyacetic acids.

Luker T, Bonnert R, Schmidt J, Sargent C, Paine SW, Thom S, Pairaudeau G, Patel A, Mohammed R, Akam E, Dougall I, Davis AM, Abbott P, Brough S, Millichip I, McInally T. Luker T, et al. Among authors: mcinally t. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3616-21. doi: 10.1016/j.bmcl.2011.04.101. Epub 2011 Apr 28. Bioorg Med Chem Lett. 2011. PMID: 21592791

10

Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.

Kurimoto A, Hashimoto K, Nakamura T, Norimura K, Ogita H, Takaku H, Bonnert R, McInally T, Wada H, Isobe Y. Kurimoto A, et al. Among authors: mcinally t. J Med Chem. 2010 Apr 8;53(7):2964-72. doi: 10.1021/jm100070n. J Med Chem. 2010. PMID: 20232824

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