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piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies.
Manuri PV, Wilson MH, Maiti SN, Mi T, Singh H, Olivares S, Dawson MJ, Huls H, Lee DA, Rao PH, Kaminski JM, Nakazawa Y, Gottschalk S, Kebriaei P, Shpall EJ, Champlin RE, Cooper LJ. Manuri PV, et al. Among authors: kebriaei p. Hum Gene Ther. 2010 Apr;21(4):427-37. doi: 10.1089/hum.2009.114. Hum Gene Ther. 2010. PMID: 19905893 Free PMC article.
A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells.
Choi Y, Yuen C, Maiti SN, Olivares S, Gibbons H, Huls H, Raphael R, Killian TC, Stark DJ, Lee DA, Torikai H, Monticello D, Kelly SS, Kebriaei P, Champlin RE, Biswal SL, Cooper LJ. Choi Y, et al. Among authors: kebriaei p. Biomed Microdevices. 2010 Oct;12(5):855-63. doi: 10.1007/s10544-010-9440-3. Biomed Microdevices. 2010. PMID: 20574820 Free PMC article.
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR.
Torikai H, Reik A, Liu PQ, Zhou Y, Zhang L, Maiti S, Huls H, Miller JC, Kebriaei P, Rabinovich B, Lee DA, Champlin RE, Bonini C, Naldini L, Rebar EJ, Gregory PD, Holmes MC, Cooper LJ. Torikai H, et al. Among authors: kebriaei p. Blood. 2012 Jun 14;119(24):5697-705. doi: 10.1182/blood-2012-01-405365. Epub 2012 Apr 24. Blood. 2012. PMID: 22535661 Free PMC article.
CARs in chronic lymphocytic leukemia -- ready to drive.
Hosing C, Kebriaei P, Wierda W, Jena B, Cooper LJN, Shpall E. Hosing C, et al. Among authors: kebriaei p. Curr Hematol Malig Rep. 2013 Mar;8(1):60-70. doi: 10.1007/s11899-012-0145-y. Curr Hematol Malig Rep. 2013. PMID: 23225251 Free PMC article. Review.
380 results