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The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models.
Schuller AG, Barry ER, Jones RD, Henry RE, Frigault MM, Beran G, Linsenmayer D, Hattersley M, Smith A, Wilson J, Cairo S, Déas O, Nicolle D, Adam A, Zinda M, Reimer C, Fawell SE, Clark EA, D'Cruz CM. Schuller AG, et al. Among authors: henry re. Clin Cancer Res. 2015 Jun 15;21(12):2811-9. doi: 10.1158/1078-0432.CCR-14-2685. Epub 2015 Mar 16. Clin Cancer Res. 2015. PMID: 25779944
A pharmacokinetic-pharmacodynamic model for the MET tyrosine kinase inhibitor, savolitinib, to explore target inhibition requirements for anti-tumour activity.
Jones RDO, Grondine M, Borodovsky A, San Martin M, DuPont M, D'Cruz C, Schuller A, Henry R, Barry E, Castriotta L, Anjum R, Petersson K, Sahota T, Ahmed GF. Jones RDO, et al. Br J Pharmacol. 2021 Feb;178(3):600-613. doi: 10.1111/bph.15301. Epub 2020 Dec 7. Br J Pharmacol. 2021. PMID: 33125717 Free article.
CBX3 regulates efficient RNA processing genome-wide.
Smallwood A, Hon GC, Jin F, Henry RE, Espinosa JM, Ren B. Smallwood A, et al. Among authors: henry re. Genome Res. 2012 Aug;22(8):1426-36. doi: 10.1101/gr.124818.111. Epub 2012 Jun 8. Genome Res. 2012. PMID: 22684280 Free PMC article.
ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.
Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. Sullivan KD, et al. Among authors: henry re. Nat Chem Biol. 2012 Jul;8(7):646-54. doi: 10.1038/nchembio.965. Epub 2012 Jun 3. Nat Chem Biol. 2012. PMID: 22660439 Free PMC article.
The p53 circuit board.
Sullivan KD, Gallant-Behm CL, Henry RE, Fraikin JL, Espinosa JM. Sullivan KD, et al. Among authors: henry re. Biochim Biophys Acta. 2012 Apr;1825(2):229-44. doi: 10.1016/j.bbcan.2012.01.004. Epub 2012 Feb 7. Biochim Biophys Acta. 2012. PMID: 22333261 Free PMC article. Review.
57 results