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Quantifying the natural history of biofilm formation in vivo during the establishment of chronic implant-associated Staphylococcus aureus osteomyelitis in mice to identify critical pathogen and host factors.
Nishitani K, Sutipornpalangkul W, de Mesy Bentley KL, Varrone JJ, Bello-Irizarry SN, Ito H, Matsuda S, Kates SL, Daiss JL, Schwarz EM. Nishitani K, et al. Among authors: varrone jj. J Orthop Res. 2015 Sep;33(9):1311-9. doi: 10.1002/jor.22907. Epub 2015 May 18. J Orthop Res. 2015. PMID: 25820925 Free PMC article.
Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis of Staphylococcus aureus megaclusters.
Varrone JJ, de Mesy Bentley KL, Bello-Irizarry SN, Nishitani K, Mack S, Hunter JG, Kates SL, Daiss JL, Schwarz EM. Varrone JJ, et al. J Orthop Res. 2014 Oct;32(10):1389-96. doi: 10.1002/jor.22672. Epub 2014 Jul 3. J Orthop Res. 2014. PMID: 24992290 Free PMC article.
Coordinated regulation of SIV replication and immune responses in the CNS.
Witwer KW, Gama L, Li M, Bartizal CM, Queen SE, Varrone JJ, Brice AK, Graham DR, Tarwater PM, Mankowski JL, Zink MC, Clements JE. Witwer KW, et al. Among authors: varrone jj. PLoS One. 2009 Dec 17;4(12):e8129. doi: 10.1371/journal.pone.0008129. PLoS One. 2009. PMID: 20019816 Free PMC article.
Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA.
Zink MC, Brice AK, Kelly KM, Queen SE, Gama L, Li M, Adams RJ, Bartizal C, Varrone J, Rabi SA, Graham DR, Tarwater PM, Mankowski JL, Clements JE. Zink MC, et al. J Infect Dis. 2010 Jul 1;202(1):161-70. doi: 10.1086/653213. J Infect Dis. 2010. PMID: 20497048 Free PMC article.