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LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, Shatseva T, Wu S, Zhang FF, Arrowsmith CH, Brown PJ, Campbell RM, Garcia BA, Barsyte-Lovejoy D, Mader M, Vedadi M. Nguyen H, et al. Among authors: zhang ff. J Biol Chem. 2015 May 29;290(22):13641-53. doi: 10.1074/jbc.M114.626861. Epub 2015 Mar 30. J Biol Chem. 2015. PMID: 25825497 Free PMC article.
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Atwell S, Brouillette CG, Conners K, Emtage S, Gheyi T, Guggino WB, Hendle J, Hunt JF, Lewis HA, Lu F, Protasevich II, Rodgers LA, Romero R, Wasserman SR, Weber PC, Wetmore D, Zhang FF, Zhao X. Atwell S, et al. Among authors: zhang ff. Protein Eng Des Sel. 2010 May;23(5):375-84. doi: 10.1093/protein/gzq004. Epub 2010 Feb 11. Protein Eng Des Sel. 2010. PMID: 20150177
Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.
Ting JP, Tung F, Antonysamy S, Wasserman S, Jones SB, Zhang FF, Espada A, Broughton H, Chalmers MJ, Woodman ME, Bina HA, Dodge JA, Benach J, Zhang A, Groshong C, Manglicmot D, Russell M, Afshar S. Ting JP, et al. Among authors: zhang a, zhang ff. PLoS One. 2018 Jan 12;13(1):e0190850. doi: 10.1371/journal.pone.0190850. eCollection 2018. PLoS One. 2018. PMID: 29329326 Free PMC article.
Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD(+)) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition.
Zhao X, Allison D, Condon B, Zhang F, Gheyi T, Zhang A, Ashok S, Russell M, MacEwan I, Qian Y, Jamison JA, Luz JG. Zhao X, et al. J Med Chem. 2016 Mar 10;59(5):2267. doi: 10.1021/acs.jmedchem.6b00130. Epub 2016 Feb 16. J Med Chem. 2016. PMID: 26882000 No abstract available.
Deciphering Binding Interactions of IL-23R with HDX-MS: Mapping Protein and Macrocyclic Dodecapeptide Ligands.
Sayago C, Gonzalez Valcarcel IC, Qian Y, Lee J, Alsina-Fernandez J, Fite NC, Carrillo JJ, Zhang FF, Chalmers MJ, Dodge JA, Broughton H, Espada A. Sayago C, et al. Among authors: zhang ff. ACS Med Chem Lett. 2018 Aug 1;9(9):912-916. doi: 10.1021/acsmedchemlett.8b00255. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258540 Free PMC article.
Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage.
Pandya P, Sayers RO, Ting JP, Morshedian S, Torres C, Cudal JS, Zhang K, Fitchett JR, Zhang Q, Zhang FF, Wang J, Durbin JD, Carrillo JJ, Espada A, Broughton H, Qian Y, Afshar S. Pandya P, et al. Among authors: zhang q, zhang k, zhang ff. PLoS One. 2020 Jun 1;15(6):e0233961. doi: 10.1371/journal.pone.0233961. eCollection 2020. PLoS One. 2020. PMID: 32479512 Free PMC article.
453 results