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iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP. Li X, et al. Among authors: qing x. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6080-5. doi: 10.1073/pnas.1505649112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918388 Free PMC article.
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, Blobel CP. Issuree PD, et al. Among authors: qing x. J Clin Invest. 2013 Feb;123(2):928-32. doi: 10.1172/JCI66168. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348744 Free PMC article.
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs JJ, Farber G, Issuree PD, Donlin L, Mcllwain DR, Mak TW, Blobel CP, Salmon JE. Qing X, et al. J Clin Invest. 2018 Apr 2;128(4):1397-1412. doi: 10.1172/JCI97650. Epub 2018 Mar 5. J Clin Invest. 2018. PMID: 29369823 Free PMC article.
A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.
Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT. Shipman WD, et al. Among authors: qing x. Sci Transl Med. 2018 Aug 15;10(454):eaap9527. doi: 10.1126/scitranslmed.aap9527. Sci Transl Med. 2018. PMID: 30111646 Free PMC article.
428 results