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HIF3A association with adiposity: the story begins before birth.
Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group. Pan H, et al. Among authors: lin x. Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26. Epigenomics. 2015. PMID: 26011824 Free PMC article.
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.
Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Lin X, et al. BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1. BMC Med. 2017. PMID: 28264723 Free PMC article.
Choice of surrogate tissue influences neonatal EWAS findings.
Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N. Lin X, et al. BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x. BMC Med. 2017. PMID: 29202839 Free PMC article.
Dichotomy in the Impact of Elevated Maternal Glucose Levels on Neonatal Epigenome.
Lim IY, Lin X, Teh AL, Wu Y, Chen L, He M, Chan SY, MacIsaac JL, Chan JKY, Tan KH, Chong MFF, Kobor MS, Godfrey KM, Meaney MJ, Lee YS, Eriksson JG, Gluckman PD, Chong YS, Karnani N. Lim IY, et al. Among authors: lin x. J Clin Endocrinol Metab. 2022 Feb 17;107(3):e1277-e1292. doi: 10.1210/clinem/dgab710. J Clin Endocrinol Metab. 2022. PMID: 34633450 Free PMC article.
ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity.
Lillycrop K, Murray R, Cheong C, Teh AL, Clarke-Harris R, Barton S, Costello P, Garratt E, Cook E, Titcombe P, Shunmuganathan B, Liew SJ, Chua YC, Lin X, Wu Y, Burdge GC, Cooper C, Inskip HM, Karnani N, Hopkins JC, Childs CE, Chavez CP, Calder PC, Yap F, Lee YS, Chong YS, Melton PE, Beilin L, Huang RC, Gluckman PD, Harvey N, Hanson MA, Holbrook JD; EpiGen Consortium; Godfrey KM. Lillycrop K, et al. Among authors: lin x. EBioMedicine. 2017 May;19:60-72. doi: 10.1016/j.ebiom.2017.03.037. Epub 2017 Apr 26. EBioMedicine. 2017. PMID: 28473239 Free PMC article. Clinical Trial.
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