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Page 1
Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract.
Hwang DY, Kohl S, Fan X, Vivante A, Chan S, Dworschak GC, Schulz J, van Eerde AM, Hilger AC, Gee HY, Pennimpede T, Herrmann BG, van de Hoek G, Renkema KY, Schell C, Huber TB, Reutter HM, Soliman NA, Stajic N, Bogdanovic R, Kehinde EO, Lifton RP, Tasic V, Lu W, Hildebrandt F. Hwang DY, et al. Among authors: van de hoek g. Hum Genet. 2015 Aug;134(8):905-16. doi: 10.1007/s00439-015-1570-5. Epub 2015 May 31. Hum Genet. 2015. PMID: 26026792 Free PMC article. Clinical Trial.
Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition.
Slaats GG, Ghosh AK, Falke LL, Le Corre S, Shaltiel IA, van de Hoek G, Klasson TD, Stokman MF, Logister I, Verhaar MC, Goldschmeding R, Nguyen TQ, Drummond IA, Hildebrandt F, Giles RH. Slaats GG, et al. Among authors: van de hoek g. PLoS Genet. 2014 Oct 23;10(10):e1004594. doi: 10.1371/journal.pgen.1004594. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25340510 Free PMC article.
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Hartill VL, van de Hoek G, Patel MP, Little R, Watson CM, Berry IR, Shoemark A, Abdelmottaleb D, Parkes E, Bacchelli C, Szymanska K, Knoers NV, Scambler PJ, Ueffing M, Boldt K, Yates R, Winyard PJ, Adler B, Moya E, Hattingh L, Shenoy A, Hogg C, Sheridan E, Roepman R, Norris D, Mitchison HM, Giles RH, Johnson CA. Hartill VL, et al. Among authors: van de hoek g. Hum Mol Genet. 2018 Feb 1;27(3):529-545. doi: 10.1093/hmg/ddx422. Hum Mol Genet. 2018. PMID: 29228333 Free PMC article.
Control of Angiogenesis via a VHL/miR-212/132 Axis.
Lei Z, Klasson TD, Brandt MM, van de Hoek G, Logister I, Cheng C, Doevendans PA, Sluijter JPG, Giles RH. Lei Z, et al. Among authors: van de hoek g. Cells. 2020 Apr 19;9(4):1017. doi: 10.3390/cells9041017. Cells. 2020. PMID: 32325871 Free PMC article.
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.
Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S. Karpanen T, et al. Among authors: van de hoek g. Circ Res. 2017 Apr 14;120(8):1263-1275. doi: 10.1161/CIRCRESAHA.116.308813. Epub 2017 Feb 8. Circ Res. 2017. PMID: 28179432 Free PMC article.
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo.
Pedrioli DM, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin JW, Marino D, Kälin RE, Leidel S, Cinelli P, Schulte-Merker S, Brändli AW, Detmar M. Pedrioli DM, et al. Among authors: van de hoek g. Mol Cell Biol. 2010 Jul;30(14):3620-34. doi: 10.1128/MCB.00185-10. Epub 2010 May 17. Mol Cell Biol. 2010. PMID: 20479124 Free PMC article.