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Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).
Rajasekaran D, Srivastava J, Ebeid K, Gredler R, Akiel M, Jariwala N, Robertson CL, Shen XN, Siddiq A, Fisher PB, Salem AK, Sarkar D. Rajasekaran D, et al. Among authors: siddiq a. Bioconjug Chem. 2015 Aug 19;26(8):1651-61. doi: 10.1021/acs.bioconjchem.5b00254. Epub 2015 Jun 25. Bioconjug Chem. 2015. PMID: 26079152 Free PMC article.
Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.
Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, Andrews WH, Sarkar D, Schaus SE, Hansen U. Grant TJ, et al. Among authors: siddiq a. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4503-8. doi: 10.1073/pnas.1121601109. Epub 2012 Mar 6. Proc Natl Acad Sci U S A. 2012. PMID: 22396589 Free PMC article.
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.
Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, Stafflinger J, Subler MA, Windle JJ, Fisher PB, Sarkar D. Srivastava J, et al. Among authors: siddiq a. Hepatology. 2012 Nov;56(5):1782-91. doi: 10.1002/hep.25868. Hepatology. 2012. PMID: 22689379 Free PMC article.
RETRACTED: Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Chen D, et al. Among authors: siddiq a. Mol Ther. 2013 Apr;21(4):758-66. doi: 10.1038/mt.2012.282. Epub 2013 Jan 15. Mol Ther. 2013. Retraction in: Mol Ther. 2023 Feb 1;31(2):599. doi: 10.1016/j.ymthe.2022.12.019. PMID: 23319057 Free PMC article. Retracted.
Astrocyte elevated gene-1 and c-Myc cooperate to promote hepatocarcinogenesis in mice.
Srivastava J, Siddiq A, Gredler R, Shen XN, Rajasekaran D, Robertson CL, Subler MA, Windle JJ, Dumur CI, Mukhopadhyay ND, Garcia D, Lai Z, Chen Y, Balaji U, Fisher PB, Sarkar D. Srivastava J, et al. Among authors: siddiq a. Hepatology. 2015 Mar;61(3):915-29. doi: 10.1002/hep.27339. Epub 2015 Jan 23. Hepatology. 2015. PMID: 25065684 Free PMC article.
AEG-1 regulates retinoid X receptor and inhibits retinoid signaling.
Srivastava J, Robertson CL, Rajasekaran D, Gredler R, Siddiq A, Emdad L, Mukhopadhyay ND, Ghosh S, Hylemon PB, Gil G, Shah K, Bhere D, Subler MA, Windle JJ, Fisher PB, Sarkar D. Srivastava J, et al. Among authors: siddiq a. Cancer Res. 2014 Aug 15;74(16):4364-77. doi: 10.1158/0008-5472.CAN-14-0421. Cancer Res. 2014. PMID: 25125681 Free PMC article.
Genetic deletion of AEG-1 prevents hepatocarcinogenesis.
Robertson CL, Srivastava J, Siddiq A, Gredler R, Emdad L, Rajasekaran D, Akiel M, Shen XN, Guo C, Giashuddin S, Wang XY, Ghosh S, Subler MA, Windle JJ, Fisher PB, Sarkar D. Robertson CL, et al. Among authors: siddiq a. Cancer Res. 2014 Nov 1;74(21):6184-93. doi: 10.1158/0008-5472.CAN-14-1357. Epub 2014 Sep 5. Cancer Res. 2014. PMID: 25193383 Free PMC article.
300 results