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Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Schludi MH, May S, Grässer FA, Rentzsch K, Kremmer E, Küpper C, Klopstock T; German Consortium for Frontotemporal Lobar Degeneration; Bavarian Brain Banking Alliance; Arzberger T, Edbauer D. Schludi MH, et al. Among authors: grasser fa. Acta Neuropathol. 2015 Oct;130(4):537-55. doi: 10.1007/s00401-015-1450-z. Epub 2015 Jun 18. Acta Neuropathol. 2015. PMID: 26085200 Free PMC article.
The LARK/RBM4a protein is highly expressed in cerebellum as compared to cerebrum.
Pfuhl T, Mamiani A, Dürr M, Welter S, Stieber J, Ankara J, Liss M, Dobner T, Schmitt A, Falkai P, Kremmer E, Jung V, Barth S, Grässer FA. Pfuhl T, et al. Among authors: grasser fa. Neurosci Lett. 2008 Oct 17;444(1):11-5. doi: 10.1016/j.neulet.2008.08.017. Epub 2008 Aug 8. Neurosci Lett. 2008. PMID: 18708123
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression.
Gross H, Hennard C, Masouris I, Cassel C, Barth S, Stober-Grässer U, Mamiani A, Moritz B, Ostareck D, Ostareck-Lederer A, Neuenkirchen N, Fischer U, Deng W, Leonhardt H, Noessner E, Kremmer E, Grässer FA. Gross H, et al. Among authors: grasser fa. PLoS One. 2012;7(8):e42106. doi: 10.1371/journal.pone.0042106. Epub 2012 Aug 3. PLoS One. 2012. PMID: 22879910 Free PMC article.
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
Mori K, Arzberger T, Grässer FA, Gijselinck I, May S, Rentzsch K, Weng SM, Schludi MH, van der Zee J, Cruts M, Van Broeckhoven C, Kremmer E, Kretzschmar HA, Haass C, Edbauer D. Mori K, et al. Among authors: grasser fa. Acta Neuropathol. 2013 Dec;126(6):881-93. doi: 10.1007/s00401-013-1189-3. Epub 2013 Oct 17. Acta Neuropathol. 2013. PMID: 24132570
109 results