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Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.
Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN. Shenoi RA, et al. Among authors: travers rj. Sci Transl Med. 2014 Oct 29;6(260):260ra150. doi: 10.1126/scitranslmed.3009427. Epub 2014 Oct 29. Sci Transl Med. 2014. PMID: 25355700
Polyphosphate, platelets, and coagulation.
Travers RJ, Smith SA, Morrissey JH. Travers RJ, et al. Int J Lab Hematol. 2015 May;37 Suppl 1(0 1):31-5. doi: 10.1111/ijlh.12349. Int J Lab Hematol. 2015. PMID: 25976958 Free PMC article. Review.
How it all starts: Initiation of the clotting cascade.
Smith SA, Travers RJ, Morrissey JH. Smith SA, et al. Among authors: travers rj. Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28. Crit Rev Biochem Mol Biol. 2015. PMID: 26018600 Free PMC article. Review.
Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.
Wijeyewickrema LC, Lameignere E, Hor L, Duncan RC, Shiba T, Travers RJ, Kapopara PR, Lei V, Smith SA, Kim H, Morrissey JH, Pike RN, Conway EM. Wijeyewickrema LC, et al. Among authors: travers rj. Blood. 2016 Sep 29;128(13):1766-76. doi: 10.1182/blood-2016-02-699561. Epub 2016 Jun 23. Blood. 2016. PMID: 27338096 Free PMC article.
Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia.
Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Cines DB, et al. Among authors: travers rj. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. Blood Adv. 2016. PMID: 29296696 Free PMC article.
Antipolyphosphate monoclonal antibodies derived from autoimmune mice.
Sedzro JC, Smith SA, Scott A, Wang Y, Travers RJ, Hemp R, Morse CN, Morrissey JH. Sedzro JC, et al. Among authors: travers rj. Res Pract Thromb Haemost. 2024 Aug 16;8(6):102550. doi: 10.1016/j.rpth.2024.102550. eCollection 2024 Aug. Res Pract Thromb Haemost. 2024. PMID: 39309228 Free PMC article.
16 results