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The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension.
Kumar R, Mickael C, Chabon J, Gebreab L, Rutebemberwa A, Garcia AR, Koyanagi DE, Sanders L, Gandjeva A, Kearns MT, Barthel L, Janssen WJ, Mauad T, Bandeira A, Schmidt E, Tuder RM, Graham BB. Kumar R, et al. Am J Respir Crit Care Med. 2015 Oct 15;192(8):998-1008. doi: 10.1164/rccm.201410-1820OC. Am J Respir Crit Care Med. 2015. PMID: 26192556 Free PMC article.
Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension.
Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM. Graham BB, et al. Among authors: kumar r. Am J Respir Cell Mol Biol. 2013 Dec;49(6):951-9. doi: 10.1165/rcmb.2012-0532OC. Am J Respir Cell Mol Biol. 2013. PMID: 23815102 Free PMC article.
Pathology of pulmonary hypertension.
Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB. Tuder RM, et al. Among authors: kumar r. Clin Chest Med. 2013 Dec;34(4):639-50. doi: 10.1016/j.ccm.2013.08.009. Epub 2013 Oct 17. Clin Chest Med. 2013. PMID: 24267295 Review.
Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Bertero T, et al. Among authors: kumar r. J Clin Invest. 2014 Aug;124(8):3514-28. doi: 10.1172/JCI74773. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960162 Free PMC article.
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. White K, et al. Among authors: kumar r. EMBO Mol Med. 2015 Jun;7(6):695-713. doi: 10.15252/emmm.201404511. EMBO Mol Med. 2015. PMID: 25825391 Free PMC article.
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Bertero T, et al. Among authors: kumar r. Cell Rep. 2015 Nov 3;13(5):1016-32. doi: 10.1016/j.celrep.2015.09.049. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565914 Free PMC article.
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Kumar R, et al. Nat Commun. 2017 May 30;8:15494. doi: 10.1038/ncomms15494. Nat Commun. 2017. PMID: 28555642 Free PMC article.
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