Saido TC - Search Results

1

Loss of neprilysin alters protein expression in the brain of Alzheimer's disease model mice.

Nilsson P, Loganathan K, Sekiguchi M, Winblad B, Iwata N, Saido TC, Tjernberg LO. Nilsson P, et al. Among authors: saido tc. Proteomics. 2015 Oct;15(19):3349-55. doi: 10.1002/pmic.201400211. Epub 2015 Aug 13. Proteomics. 2015. PMID: 26194619

2

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition.

Iwata N, Tsubuki S, Takaki Y, Watanabe K, Sekiguchi M, Hosoki E, Kawashima-Morishima M, Lee HJ, Hama E, Sekine-Aizawa Y, Saido TC. Iwata N, et al. Among authors: saido tc. Nat Med. 2000 Feb;6(2):143-50. doi: 10.1038/72237. Nat Med. 2000. PMID: 10655101

3

Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T. Takeuchi A, et al. Among authors: saido tc. Am J Pathol. 2000 Jul;157(1):331-9. doi: 10.1016/s0002-9440(10)64544-0. Am J Pathol. 2000. PMID: 10880403 Free PMC article.

4

Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.

Takaki Y, Iwata N, Tsubuki S, Taniguchi S, Toyoshima S, Lu B, Gerard NP, Gerard C, Lee HJ, Shirotani K, Saido TC. Takaki Y, et al. Among authors: saido tc. J Biochem. 2000 Dec;128(6):897-902. doi: 10.1093/oxfordjournals.jbchem.a022839. J Biochem. 2000. PMID: 11098130 Free article.

5

Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum.

Sekine-Aizawa Y, Hama E, Watanabe K, Tsubuki S, Kanai-Azuma M, Kanai Y, Arai H, Aizawa H, Iwata N, Saido TC. Sekine-Aizawa Y, et al. Among authors: saido tc. Eur J Neurosci. 2001 Mar;13(5):935-48. doi: 10.1046/j.0953-816x.2001.01462.x. Eur J Neurosci. 2001. PMID: 11264666

6

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, Kiryu-Seo S, Kiyama H, Iwata H, Tomita T, Iwatsubo T, Saido TC. Shirotani K, et al. Among authors: saido tc. J Biol Chem. 2001 Jun 15;276(24):21895-901. doi: 10.1074/jbc.M008511200. Epub 2001 Mar 6. J Biol Chem. 2001. PMID: 11278416 Free article.

7

Metabolic regulation of brain Abeta by neprilysin.

Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC. Iwata N, et al. Among authors: saido tc. Science. 2001 May 25;292(5521):1550-2. doi: 10.1126/science.1059946. Science. 2001. PMID: 11375493

8

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC. Fukami S, et al. Among authors: saido tc. Neurosci Res. 2002 May;43(1):39-56. doi: 10.1016/s0168-0102(02)00015-9. Neurosci Res. 2002. PMID: 12074840

9

In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.

Takahashi M, Fukami S, Iwata N, Inoue K, Itohara S, Itoh H, Haraoka J, Saido T. Takahashi M, et al. Pharmacol Res. 2002 Aug;46(2):155-63. doi: 10.1016/s1043-6618(02)00081-6. Pharmacol Res. 2002. PMID: 12220955

10

Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC. Iwata N, et al. Among authors: saido tc. J Neurosci Res. 2002 Nov 1;70(3):493-500. doi: 10.1002/jnr.10390. J Neurosci Res. 2002. PMID: 12391610

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