Schofield CJ - Search Results

1

The broad spectrum 2-oxoglutarate oxygenase inhibitor N-oxalylglycine is present in rhubarb and spinach leaves.

Al-Qahtani K, Jabeen B, Sekirnik R, Riaz N, Claridge TDW, Schofield CJ, McCullagh JSO. Al-Qahtani K, et al. Among authors: schofield cj. Phytochemistry. 2015 Sep;117:456-461. doi: 10.1016/j.phytochem.2015.06.028. Epub 2015 Jul 18. Phytochemistry. 2015. PMID: 26196940

2

Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides.

Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Baldwin JE, et al. Among authors: schofield cj. Int J Pept Protein Res. 1994 Feb;43(2):180-3. doi: 10.1111/j.1399-3011.1994.tb00520.x. Int J Pept Protein Res. 1994. PMID: 8200737

3

Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.

Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1998 Dec 15;37(50):17506-13. doi: 10.1021/bi9816249. Biochemistry. 1998. PMID: 9860865

4

Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.

Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1999 Jun 22;38(25):7989-98. doi: 10.1021/bi990098y. Biochemistry. 1999. PMID: 10387042

5

Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.

Kershaw NJ, Mukherji M, MacKinnon CH, Claridge TD, Odell B, Wierzbicki AS, Lloyd MD, Schofield CJ. Kershaw NJ, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2545-8. doi: 10.1016/s0960-894x(01)00494-2. Bioorg Med Chem Lett. 2001. PMID: 11549466

6

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

Hon WC, Wilson MI, Harlos K, Claridge TD, Schofield CJ, Pugh CW, Maxwell PH, Ratcliffe PJ, Stuart DI, Jones EY. Hon WC, et al. Among authors: schofield cj. Nature. 2002 Jun 27;417(6892):975-8. doi: 10.1038/nature00767. Epub 2002 Jun 5. Nature. 2002. PMID: 12050673

7

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.

McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE, Schofield CJ. McNeill LA, et al. Among authors: schofield cj. Biochem J. 2002 Nov 1;367(Pt 3):571-5. doi: 10.1042/BJ20021162. Biochem J. 2002. PMID: 12215170 Free PMC article.

8

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.

Welford RW, Turnbull JJ, Claridge TD, Prescott AG, Schofield CJ. Welford RW, et al. Among authors: schofield cj. Chem Commun (Camb). 2001 Sep 21;(18):1828-9. doi: 10.1039/b105576n. Chem Commun (Camb). 2001. PMID: 12240335

9

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate.

McNeill LA, Flashman E, Buck MR, Hewitson KS, Clifton IJ, Jeschke G, Claridge TD, Ehrismann D, Oldham NJ, Schofield CJ. McNeill LA, et al. Among authors: schofield cj. Mol Biosyst. 2005 Oct;1(4):321-4. doi: 10.1039/b511249b. Epub 2005 Aug 22. Mol Biosyst. 2005. PMID: 16880998

10

Expanding chemical biology of 2-oxoglutarate oxygenases.

Loenarz C, Schofield CJ. Loenarz C, et al. Among authors: schofield cj. Nat Chem Biol. 2008 Mar;4(3):152-6. doi: 10.1038/nchembio0308-152. Nat Chem Biol. 2008. PMID: 18277970

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