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Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1.
Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, Schang LM, Kirschning A, Müller R, Guzman CA, Kaderali L, Randall G, Meuleman P, Ploss A, Pietschmann T. Perin PM, et al. Among authors: brown rj. Hepatology. 2016 Jan;63(1):49-62. doi: 10.1002/hep.28111. Epub 2015 Oct 9. Hepatology. 2016. PMID: 26248546 Free PMC article.
Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution.
Brown RJ, Koutsoudakis G, Urbanowicz RA, Mirza D, Ginkel C, Riebesehl N, Calland N, Albecka A, Price L, Hudson N, Descamps V, Backx M, McClure CP, Duverlie G, Pecheur EI, Dubuisson J, Perez-del-Pulgar S, Forns X, Steinmann E, Tarr AW, Pietschmann T, Ball JK. Brown RJ, et al. J Virol. 2014 Jan;88(1):667-78. doi: 10.1128/JVI.01745-13. Epub 2013 Oct 30. J Virol. 2014. PMID: 24173227 Free PMC article.
Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.
Irving WL, Rupp D, McClure CP, Than LM, Titman A, Ball JK, Steinmann E, Bartenschlager R, Pietschmann T, Brown RJ. Irving WL, et al. Among authors: brown rj. Antiviral Res. 2014 Oct;110:52-9. doi: 10.1016/j.antiviral.2014.07.009. Epub 2014 Jul 22. Antiviral Res. 2014. PMID: 25057759
Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses.
Pfaender S, Cavalleri JM, Walter S, Doerrbecker J, Campana B, Brown RJ, Burbelo PD, Postel A, Hahn K, Anggakusuma, Riebesehl N, Baumgärtner W, Becher P, Heim MH, Pietschmann T, Feige K, Steinmann E. Pfaender S, et al. Among authors: brown rj. Hepatology. 2015 Feb;61(2):447-59. doi: 10.1002/hep.27440. Epub 2015 Jan 5. Hepatology. 2015. PMID: 25212983
747 results