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886 results

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Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.
Boehm AL, Sen M, Seethala R, Gooding WE, Freilino M, Wong SM, Wang S, Johnson DE, Grandis JR. Boehm AL, et al. Among authors: sen m. Mol Pharmacol. 2008 Jun;73(6):1632-42. doi: 10.1124/mol.107.044636. Epub 2008 Mar 6. Mol Pharmacol. 2008. PMID: 18326051 Free PMC article.
Lack of toxicity of a STAT3 decoy oligonucleotide.
Sen M, Tosca PJ, Zwayer C, Ryan MJ, Johnson JD, Knostman KA, Giclas PC, Peggins JO, Tomaszewski JE, McMurray TP, Li C, Leibowitz MS, Ferris RL, Gooding WE, Thomas SM, Johnson DE, Grandis JR. Sen M, et al. Cancer Chemother Pharmacol. 2009 May;63(6):983-95. doi: 10.1007/s00280-008-0823-6. Epub 2008 Sep 3. Cancer Chemother Pharmacol. 2009. PMID: 18766340 Free PMC article.
Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death.
Li C, Zang Y, Sen M, Leeman-Neill RJ, Man DS, Grandis JR, Johnson DE. Li C, et al. Among authors: sen m. Mol Cancer Ther. 2009 Aug;8(8):2211-20. doi: 10.1158/1535-7163.MCT-09-0327. Epub 2009 Jul 28. Mol Cancer Ther. 2009. PMID: 19638453 Free PMC article.
Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3.
Leeman-Neill RJ, Wheeler SE, Singh SV, Thomas SM, Seethala RR, Neill DB, Panahandeh MC, Hahm ER, Joyce SC, Sen M, Cai Q, Freilino ML, Li C, Johnson DE, Grandis JR. Leeman-Neill RJ, et al. Among authors: sen m. Carcinogenesis. 2009 Nov;30(11):1848-56. doi: 10.1093/carcin/bgp211. Epub 2009 Sep 16. Carcinogenesis. 2009. PMID: 19762335 Free PMC article.
Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer.
Bhola NE, Freilino ML, Joyce SC, Sen M, Thomas SM, Sahu A, Cassell A, Chen CS, Grandis JR. Bhola NE, et al. Among authors: sen m. Mol Cancer Ther. 2012 Jun;11(6):1236-46. doi: 10.1158/1535-7163.MCT-11-0936. Epub 2012 Apr 5. Mol Cancer Ther. 2012. PMID: 22491800 Free PMC article.
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.
Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, Ly D, Rapireddy S, Etter JP, Li PK, Wang L, Chiosea S, Seethala RR, Gooding WE, Chen X, Kaminski N, Pandit K, Johnson DE, Grandis JR. Sen M, et al. Cancer Discov. 2012 Aug;2(8):694-705. doi: 10.1158/2159-8290.CD-12-0191. Epub 2012 Jun 20. Cancer Discov. 2012. PMID: 22719020 Free PMC article. Clinical Trial.
Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.
Sen M, Joyce S, Panahandeh M, Li C, Thomas SM, Maxwell J, Wang L, Gooding WE, Johnson DE, Grandis JR. Sen M, et al. Clin Cancer Res. 2012 Sep 15;18(18):4986-96. doi: 10.1158/1078-0432.CCR-12-0792. Epub 2012 Jul 23. Clin Cancer Res. 2012. PMID: 22825581 Free PMC article.
886 results