Shou W - Search Results

1

Coupling Laser Diode Thermal Desorption with Acoustic Sample Deposition to Improve Throughput of Mass Spectrometry-Based Screening.

Haarhoff Z, Wagner A, Picard P, Drexler DM, Zvyaga T, Shou W. Haarhoff Z, et al. Among authors: shou w. J Biomol Screen. 2016 Feb;21(2):165-75. doi: 10.1177/1087057115607184. Epub 2015 Sep 29. J Biomol Screen. 2016. PMID: 26420787

2

A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen.

Kieltyka K, Zhang J, Li S, Vath M, Baglieri C, Ferraro C, Zvyaga TA, Drexler DM, Weller HN, Shou WZ. Kieltyka K, et al. Rapid Commun Mass Spectrom. 2009 Jun;23(11):1579-91. doi: 10.1002/rcm.4037. Rapid Commun Mass Spectrom. 2009. PMID: 19399765

3

An integrated bioanalytical platform for supporting high-throughput serum protein binding screening.

Zhang J, Shou WZ, Vath M, Kieltyka K, Maloney J, Elvebak L, Stewart J, Herbst J, Weller HN. Zhang J, et al. Rapid Commun Mass Spectrom. 2010 Dec 30;24(24):3593-601. doi: 10.1002/rcm.4817. Rapid Commun Mass Spectrom. 2010. PMID: 21080511

4

Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.

Wagner AD, Kolb JM, Ozbal CC, Herbst JJ, Olah TV, Weller HN, Zvyaga TA, Shou WZ. Wagner AD, et al. Rapid Commun Mass Spectrom. 2011 May 15;25(9):1231-40. doi: 10.1002/rcm.4984. Rapid Commun Mass Spectrom. 2011. PMID: 21488121

5

Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1).

Wu SC, Yoon D, Chin J, van Kirk K, Seethala R, Golla R, He B, Harrity T, Kunselman LK, Morgan NN, Ponticiello RP, Taylor JR, Zebo R, Harper TW, Li W, Wang M, Zhang L, Sleczka BG, Nayeem A, Sheriff S, Camac DM, Morin PE, Everlof JG, Li YX, Ferraro CA, Kieltyka K, Shou W, Vath MB, Zvyaga TA, Gordon DA, Robl JA. Wu SC, et al. Among authors: shou w. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6693-8. doi: 10.1016/j.bmcl.2011.09.058. Epub 2011 Sep 21. Bioorg Med Chem Lett. 2011. PMID: 21983444

6

Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays.

Zhang J, Maloney J, Drexler DM, Cai X, Stewart J, Mayer C, Herbst J, Weller H, Shou WZ. Zhang J, et al. Bioanalysis. 2012 Mar;4(5):581-93. doi: 10.4155/bio.12.2. Bioanalysis. 2012. PMID: 22409555

7

Approach to improve compound recovery in a high-throughput Caco-2 permeability assay supported by liquid chromatography-tandem mass spectrometry.

Cai X, Walker A, Cheng C, Paiva A, Li Y, Kolb J, Herbst J, Shou W, Weller H. Cai X, et al. Among authors: shou w. J Pharm Sci. 2012 Aug;101(8):2755-62. doi: 10.1002/jps.23194. Epub 2012 May 18. J Pharm Sci. 2012. PMID: 22611052

8

Recent development in software and automation tools for high-throughput discovery bioanalysis.

Shou WZ, Zhang J. Shou WZ, et al. Bioanalysis. 2012 May;4(9):1097-109. doi: 10.4155/bio.12.51. Bioanalysis. 2012. PMID: 22612689 Review.

9

A high-speed liquid chromatography/tandem mass spectrometry platform using multiplexed multiple-injection chromatography controlled by single software and its application in discovery ADME screening.

Zhang J, Vath M, Ferraro C, Li Y, Murphy K, Zvyaga T, Weller H, Shou W. Zhang J, et al. Among authors: shou w. Rapid Commun Mass Spectrom. 2013 Apr 15;27(7):731-7. doi: 10.1002/rcm.6514. Rapid Commun Mass Spectrom. 2013. PMID: 23495019

10

Application of Cassette Ultracentrifugation Using Non-labeled Compounds and Liquid Chromatography-Tandem Mass Spectrometry Analysis for High-Throughput Protein Binding Determination.

Kieltyka K, McAuliffe B, Cianci C, Drexler DM, Shou W, Zhang J. Kieltyka K, et al. Among authors: shou w. J Pharm Sci. 2016 Mar;105(3):1036-42. doi: 10.1016/S0022-3549(15)00177-X. Epub 2016 Jan 27. J Pharm Sci. 2016. PMID: 26886323

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