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321 results

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Page 1
Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas.
Verreault M, Schmitt C, Goldwirt L, Pelton K, Haidar S, Levasseur C, Guehennec J, Knoff D, Labussière M, Marie Y, Ligon AH, Mokhtari K, Hoang-Xuan K, Sanson M, Alexander BM, Wen PY, Delattre JY, Ligon KL, Idbaih A. Verreault M, et al. Among authors: ligon ah, ligon kl. Clin Cancer Res. 2016 Mar 1;22(5):1185-96. doi: 10.1158/1078-0432.CCR-15-1015. Epub 2015 Oct 19. Clin Cancer Res. 2016. PMID: 26482041 Free PMC article.
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.
Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA. Maher EA, et al. Among authors: ligon kl. Cancer Res. 2006 Dec 1;66(23):11502-13. doi: 10.1158/0008-5472.CAN-06-2072. Epub 2006 Nov 17. Cancer Res. 2006. PMID: 17114236
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J, Kieran M, Wen PY. Kesari S, et al. Among authors: ligon kl. Neuro Oncol. 2008 Jun;10(3):300-8. doi: 10.1215/15228517-2008-005. Epub 2008 Apr 10. Neuro Oncol. 2008. PMID: 18403492 Free PMC article. Clinical Trial.
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.
Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Schüller U, et al. Among authors: ligon ah, ligon kl. Cancer Cell. 2008 Aug 12;14(2):123-34. doi: 10.1016/j.ccr.2008.07.005. Cancer Cell. 2008. PMID: 18691547 Free PMC article.
Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
Kesari S, Schiff D, Drappatz J, LaFrankie D, Doherty L, Macklin EA, Muzikansky A, Santagata S, Ligon KL, Norden AD, Ciampa A, Bradshaw J, Levy B, Radakovic G, Ramakrishna N, Black PM, Wen PY. Kesari S, et al. Among authors: ligon kl. Clin Cancer Res. 2009 Jan 1;15(1):330-7. doi: 10.1158/1078-0432.CCR-08-0888. Clin Cancer Res. 2009. PMID: 19118062 Clinical Trial.
Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).
Wen PY, Yung WK, Lamborn KR, Norden AD, Cloughesy TF, Abrey LE, Fine HA, Chang SM, Robins HI, Fink K, Deangelis LM, Mehta M, Di Tomaso E, Drappatz J, Kesari S, Ligon KL, Aldape K, Jain RK, Stiles CD, Egorin MJ, Prados MD. Wen PY, et al. Among authors: ligon kl. Neuro Oncol. 2009 Dec;11(6):853-60. doi: 10.1215/15228517-2009-010. Neuro Oncol. 2009. PMID: 19293394 Free PMC article. Clinical Trial.
Array-based genomics in glioma research.
Idbaih A, Crinière E, Ligon KL, Delattre O, Delattre JY. Idbaih A, et al. Among authors: ligon kl. Brain Pathol. 2010 Jan;20(1):28-38. doi: 10.1111/j.1750-3639.2009.00274.x. Epub 2009 Mar 3. Brain Pathol. 2010. PMID: 19298630 Free PMC article. Review.
CRX is a diagnostic marker of retinal and pineal lineage tumors.
Santagata S, Maire CL, Idbaih A, Geffers L, Correll M, Holton K, Quackenbush J, Ligon KL. Santagata S, et al. Among authors: ligon kl. PLoS One. 2009 Nov 20;4(11):e7932. doi: 10.1371/journal.pone.0007932. PLoS One. 2009. PMID: 19936203 Free PMC article.
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
Drappatz J, Norden AD, Wong ET, Doherty LM, Lafrankie DC, Ciampa A, Kesari S, Sceppa C, Gerard M, Phan P, Schiff D, Batchelor TT, Ligon KL, Young G, Muzikansky A, Weiss SE, Wen PY. Drappatz J, et al. Among authors: ligon kl. Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):85-90. doi: 10.1016/j.ijrobp.2009.07.1741. Epub 2010 Feb 4. Int J Radiat Oncol Biol Phys. 2010. PMID: 20137866 Clinical Trial.
321 results