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KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. major transmitted by its natural vector Phlebotomus duboscqi.
Gomes R, Teixeira C, Oliveira F, Lawyer PG, Elnaiem DE, Meneses C, Goto Y, Bhatia A, Howard RF, Reed SG, Valenzuela JG, Kamhawi S. Gomes R, et al. Among authors: reed sg. PLoS Negl Trop Dis. 2012;6(4):e1610. doi: 10.1371/journal.pntd.0001610. Epub 2012 Apr 3. PLoS Negl Trop Dis. 2012. PMID: 22509423 Free PMC article.
Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis.
Cecílio P, Pérez-Cabezas B, Fernández L, Moreno J, Carrillo E, Requena JM, Fichera E, Reed SG, Coler RN, Kamhawi S, Oliveira F, Valenzuela JG, Gradoni L, Glueck R, Gupta G, Cordeiro-da-Silva A. Cecílio P, et al. Among authors: reed sg. PLoS Negl Trop Dis. 2017 Nov 27;11(11):e0005951. doi: 10.1371/journal.pntd.0005951. eCollection 2017 Nov. PLoS Negl Trop Dis. 2017. PMID: 29176865 Free PMC article.
A defined subunit vaccine that protects against vector-borne visceral leishmaniasis.
Duthie MS, Pereira L, Favila M, Hofmeyer KA, Reed SJ, Metangmo S, Townsend S, Laurance JD, Picone A, Misquith A, Hossain F, Ghosh P, Khan MAA, Guderian J, Bailor HR, Liang H, Vergara J, Oliveira F, Howard RF, Kamhawi S, Mondal D, Coler RN, Valenzuela JG, Reed SG. Duthie MS, et al. Among authors: reed sj, reed sg. NPJ Vaccines. 2017 Aug 21;2:23. doi: 10.1038/s41541-017-0025-5. eCollection 2017. NPJ Vaccines. 2017. PMID: 29263878 Free PMC article.
A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates.
Oliveira F, Rowton E, Aslan H, Gomes R, Castrovinci PA, Alvarenga PH, Abdeladhim M, Teixeira C, Meneses C, Kleeman LT, Guimarães-Costa AB, Rowland TE, Gilmore D, Doumbia S, Reed SG, Lawyer PG, Andersen JF, Kamhawi S, Valenzuela JG. Oliveira F, et al. Among authors: reed sg. Sci Transl Med. 2015 Jun 3;7(290):290ra90. doi: 10.1126/scitranslmed.aaa3043. Sci Transl Med. 2015. PMID: 26041707
Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis.
Coler RN, Skeiky YA, Bernards K, Greeson K, Carter D, Cornellison CD, Modabber F, Campos-Neto A, Reed SG. Coler RN, et al. Among authors: reed sg. Infect Immun. 2002 Aug;70(8):4215-25. doi: 10.1128/IAI.70.8.4215-4225.2002. Infect Immun. 2002. PMID: 12117930 Free PMC article.
Second-generation vaccines against leishmaniasis.
Coler RN, Reed SG. Coler RN, et al. Among authors: reed sg. Trends Parasitol. 2005 May;21(5):244-9. doi: 10.1016/j.pt.2005.03.006. Trends Parasitol. 2005. PMID: 15837614 Review.
457 results