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Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.
Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA. Huang X, et al. Among authors: chakrabarti g. Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006. Cancer Cell. 2016. PMID: 27960087 Free PMC article.
Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC.
Madajewski B, Boatman MA, Chakrabarti G, Boothman DA, Bey EA. Madajewski B, et al. Among authors: chakrabarti g. Mol Cancer Res. 2016 Jan;14(1):14-25. doi: 10.1158/1541-7786.MCR-15-0207-T. Epub 2015 Nov 9. Mol Cancer Res. 2016. PMID: 26553038 Free PMC article.
Using DNA devices to track anticancer drug activity.
Kahanda D, Chakrabarti G, Mcwilliams MA, Boothman DA, Slinker JD. Kahanda D, et al. Among authors: chakrabarti g. Biosens Bioelectron. 2016 Jun 15;80:647-653. doi: 10.1016/j.bios.2016.02.026. Epub 2016 Feb 12. Biosens Bioelectron. 2016. PMID: 26901461 Free PMC article.
NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer.
Li LS, Reddy S, Lin ZH, Liu S, Park H, Chun SG, Bornmann WG, Thibodeaux J, Yan J, Chakrabarti G, Xie XJ, Sumer BD, Boothman DA, Yordy JS. Li LS, et al. Among authors: chakrabarti g. Mol Cancer Ther. 2016 Jul;15(7):1757-67. doi: 10.1158/1535-7163.MCT-15-0765. Epub 2016 Apr 12. Mol Cancer Ther. 2016. PMID: 27196777 Free PMC article.
Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.
Cao L, Li LS, Spruell C, Xiao L, Chakrabarti G, Bey EA, Reinicke KE, Srougi MC, Moore Z, Dong Y, Vo P, Kabbani W, Yang CR, Wang X, Fattah F, Morales JC, Motea EA, Bornmann WG, Yordy JS, Boothman DA. Cao L, et al. Among authors: chakrabarti g. Antioxid Redox Signal. 2014 Jul 10;21(2):237-50. doi: 10.1089/ars.2013.5462. Epub 2014 Apr 3. Antioxid Redox Signal. 2014. PMID: 24512128 Free PMC article.
100 results