Gerson SL - Search Results

1

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA. Chakrabarti G, et al. Among authors: gerson sl. Sci Rep. 2015 Nov 25;5:17066. doi: 10.1038/srep17066. Sci Rep. 2015. PMID: 26602448 Free PMC article.

2

Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.

Liu L, Gerson SL. Liu L, et al. Among authors: gerson sl. Curr Opin Investig Drugs. 2004 Jun;5(6):623-7. Curr Opin Investig Drugs. 2004. PMID: 15242251 Review.

3

Base excision repair as a therapeutic target in colon cancer.

Liu L, Nakatsuru Y, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2002 Sep;8(9):2985-91. Clin Cancer Res. 2002. PMID: 12231545

4

Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts.

Liu L, Yan L, Donze JR, Gerson SL. Liu L, et al. Among authors: gerson sl. Mol Cancer Ther. 2003 Oct;2(10):1061-6. Mol Cancer Ther. 2003. PMID: 14578471

5

Targeted modulation of MGMT: clinical implications.

Liu L, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2006 Jan 15;12(2):328-31. doi: 10.1158/1078-0432.CCR-05-2543. Clin Cancer Res. 2006. PMID: 16428468 Review.

6

Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.

Liu L, Taverna P, Whitacre CM, Chatterjee S, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 1999 Oct;5(10):2908-17. Clin Cancer Res. 1999. PMID: 10537360

7

Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.

Bulgar AD, Weeks LD, Miao Y, Yang S, Xu Y, Guo C, Markowitz S, Oleinick N, Gerson SL, Liu L. Bulgar AD, et al. Among authors: gerson sl. Cell Death Dis. 2012 Jan 12;3(1):e252. doi: 10.1038/cddis.2011.135. Cell Death Dis. 2012. PMID: 22237209 Free PMC article.

8

Repopulating defect of mismatch repair-deficient hematopoietic stem cells.

Reese JS, Liu L, Gerson SL. Reese JS, et al. Among authors: gerson sl. Blood. 2003 Sep 1;102(5):1626-33. doi: 10.1182/blood-2002-10-3035. Epub 2003 May 1. Blood. 2003. PMID: 12730104 Free article.

9

Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha.

Yan L, Bulgar A, Miao Y, Mahajan V, Donze JR, Gerson SL, Liu L. Yan L, et al. Among authors: gerson sl. Clin Cancer Res. 2007 Mar 1;13(5):1532-9. doi: 10.1158/1078-0432.CCR-06-1595. Clin Cancer Res. 2007. PMID: 17332299

10

Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair.

Wang Y, Liu L, Wu C, Bulgar A, Somoza E, Zhu W, Gerson SL. Wang Y, et al. Among authors: gerson sl. Nucl Med Biol. 2009 Nov;36(8):975-83. doi: 10.1016/j.nucmedbio.2009.07.007. Epub 2009 Oct 3. Nucl Med Biol. 2009. PMID: 19875055 Free PMC article.

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