Butte AJ - Search Results

1

Leveraging big data to transform target selection and drug discovery.

Chen B, Butte AJ. Chen B, et al. Among authors: butte aj. Clin Pharmacol Ther. 2016 Mar;99(3):285-97. doi: 10.1002/cpt.318. Clin Pharmacol Ther. 2016. PMID: 26659699 Free PMC article. Review.

2

Data-driven methods to discover molecular determinants of serious adverse drug events.

Chiang AP, Butte AJ. Chiang AP, et al. Among authors: butte aj. Clin Pharmacol Ther. 2009 Mar;85(3):259-68. doi: 10.1038/clpt.2008.274. Epub 2009 Jan 28. Clin Pharmacol Ther. 2009. PMID: 19177064 Free PMC article. Review.

3

Systematic evaluation of drug-disease relationships to identify leads for novel drug uses.

Chiang AP, Butte AJ. Chiang AP, et al. Among authors: butte aj. Clin Pharmacol Ther. 2009 Nov;86(5):507-10. doi: 10.1038/clpt.2009.103. Epub 2009 Jul 1. Clin Pharmacol Ther. 2009. PMID: 19571805 Free PMC article.

4

Predicting adverse drug reactions using publicly available PubChem BioAssay data.

Pouliot Y, Chiang AP, Butte AJ. Pouliot Y, et al. Among authors: butte aj. Clin Pharmacol Ther. 2011 Jul;90(1):90-9. doi: 10.1038/clpt.2011.81. Epub 2011 May 25. Clin Pharmacol Ther. 2011. PMID: 21613989 Free PMC article.

5

Translational bioinformatics: data-driven drug discovery and development.

Butte AJ, Ito S. Butte AJ, et al. Clin Pharmacol Ther. 2012 Jun;91(6):949-52. doi: 10.1038/clpt.2012.55. Clin Pharmacol Ther. 2012. PMID: 22609903

6

Network medicine in disease analysis and therapeutics.

Chen B, Butte AJ. Chen B, et al. Among authors: butte aj. Clin Pharmacol Ther. 2013 Dec;94(6):627-9. doi: 10.1038/clpt.2013.181. Clin Pharmacol Ther. 2013. PMID: 24241637 Free PMC article.

7

Relating Chemical Structure to Cellular Response: An Integrative Analysis of Gene Expression, Bioactivity, and Structural Data Across 11,000 Compounds.

Chen B, Greenside P, Paik H, Sirota M, Hadley D, Butte AJ. Chen B, et al. Among authors: butte aj. CPT Pharmacometrics Syst Pharmacol. 2015 Oct;4(10):576-84. doi: 10.1002/psp4.12009. Epub 2015 Sep 29. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26535158 Free PMC article.

8

DO CANCER CLINICAL TRIAL POPULATIONS TRULY REPRESENT CANCER PATIENTS? A COMPARISON OF OPEN CLINICAL TRIALS TO THE CANCER GENOME ATLAS.

Geifman N, Butte AJ. Geifman N, et al. Among authors: butte aj. Pac Symp Biocomput. 2016;21:309-20. Pac Symp Biocomput. 2016. PMID: 26776196 Free PMC article.

9

Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses.

Paik H, Chen B, Sirota M, Hadley D, Butte AJ. Paik H, et al. Among authors: butte aj. CPT Pharmacometrics Syst Pharmacol. 2016 Nov;5(11):599-607. doi: 10.1002/psp4.12108. Epub 2016 Nov 14. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27860440 Free PMC article.

10

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma.

Pessetto ZY, Chen B, Alturkmani H, Hyter S, Flynn CA, Baltezor M, Ma Y, Rosenthal HG, Neville KA, Weir SJ, Butte AJ, Godwin AK. Pessetto ZY, et al. Among authors: butte aj. Oncotarget. 2017 Jan 17;8(3):4079-4095. doi: 10.18632/oncotarget.13385. Oncotarget. 2017. PMID: 27863422 Free PMC article.

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