Zhou K - Search Results

1

Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model.

Zhou K, Nguyen LH, Miller JB, Yan Y, Kos P, Xiong H, Li L, Hao J, Minnig JT, Zhu H, Siegwart DJ. Zhou K, et al. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):520-5. doi: 10.1073/pnas.1520756113. Epub 2016 Jan 4. Proc Natl Acad Sci U S A. 2016. PMID: 26729861 Free PMC article.

2

Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells.

Yan Y, Liu L, Xiong H, Miller JB, Zhou K, Kos P, Huffman KE, Elkassih S, Norman JW, Carstens R, Kim J, Minna JD, Siegwart DJ. Yan Y, et al. Among authors: zhou k. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5702-10. doi: 10.1073/pnas.1606886113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621434 Free PMC article.

3

Intercalation-mediated nucleic acid nanoparticles for siRNA delivery.

Zhou K, Kos P, Yan Y, Xiong H, Min YL, Kinghorn KA, Minnig JT, Miller JB, Siegwart DJ. Zhou K, et al. Chem Commun (Camb). 2016 Oct 6;52(82):12155-12158. doi: 10.1039/c6cc06024b. Chem Commun (Camb). 2016. PMID: 27711272

4

Hydrophobic Domain Structure of Linear-Dendritic Poly(ethylene glycol) Lipids Affects RNA Delivery of Lipid Nanoparticles.

Zhou K, Johnson LT, Xiong H, Barrios S, Minnig JT, Yan Y, Abram B, Yu X, Siegwart DJ. Zhou K, et al. Mol Pharm. 2020 May 4;17(5):1575-1585. doi: 10.1021/acs.molpharmaceut.9b01288. Epub 2020 Apr 23. Mol Pharm. 2020. PMID: 32267707

5

Activatable Water-Soluble Probes Enhance Tumor Imaging by Responding to Dysregulated pH and Exhibiting High Tumor-to-Liver Fluorescence Emission Contrast.

Xiong H, Kos P, Yan Y, Zhou K, Miller JB, Elkassih S, Siegwart DJ. Xiong H, et al. Among authors: zhou k. Bioconjug Chem. 2016 Jul 20;27(7):1737-44. doi: 10.1021/acs.bioconjchem.6b00242. Epub 2016 Jun 20. Bioconjug Chem. 2016. PMID: 27285307

6

Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors.

Yan Y, Zhou K, Xiong H, Miller JB, Motea EA, Boothman DA, Liu L, Siegwart DJ. Yan Y, et al. Among authors: zhou k. Biomaterials. 2017 Feb;118:84-93. doi: 10.1016/j.biomaterials.2016.12.001. Epub 2016 Dec 2. Biomaterials. 2017. PMID: 27974266 Free PMC article.

7

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.

Miller JB, Zhang S, Kos P, Xiong H, Zhou K, Perelman SS, Zhu H, Siegwart DJ. Miller JB, et al. Among authors: zhou k. Angew Chem Int Ed Engl. 2017 Jan 19;56(4):1059-1063. doi: 10.1002/anie.201610209. Epub 2016 Dec 16. Angew Chem Int Ed Engl. 2017. PMID: 27981708 Free PMC article.

8

High-Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size-Controlled pH-Activatable Water-Soluble Probes.

Xiong H, Zuo H, Yan Y, Occhialini G, Zhou K, Wan Y, Siegwart DJ. Xiong H, et al. Among authors: zhou k. Adv Mater. 2017 Aug;29(29). doi: 10.1002/adma.201700131. Epub 2017 May 31. Adv Mater. 2017. PMID: 28563903

9

Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration.

Zhang S, Nguyen LH, Zhou K, Tu HC, Sehgal A, Nassour I, Li L, Gopal P, Goodman J, Singal AG, Yopp A, Zhang Y, Siegwart DJ, Zhu H. Zhang S, et al. Among authors: zhou k. Gastroenterology. 2018 Apr;154(5):1421-1434. doi: 10.1053/j.gastro.2017.12.013. Epub 2017 Dec 21. Gastroenterology. 2018. PMID: 29274368 Free PMC article.

10

Development of Cationic Quaternary Ammonium Sulfonamide Amino Lipids for Nucleic Acid Delivery.

Miller JB, Kos P, Tieu V, Zhou K, Siegwart DJ. Miller JB, et al. Among authors: zhou k. ACS Appl Mater Interfaces. 2018 Jan 24;10(3):2302-2311. doi: 10.1021/acsami.7b15982. Epub 2018 Jan 11. ACS Appl Mater Interfaces. 2018. PMID: 29286232

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