Godbout JP - Search Results

1

Aging with a traumatic brain injury: Could behavioral morbidities and endocrine symptoms be influenced by microglial priming?

Ziebell JM, Rowe RK, Muccigrosso MM, Reddaway JT, Adelson PD, Godbout JP, Lifshitz J. Ziebell JM, et al. Among authors: godbout jp. Brain Behav Immun. 2017 Jan;59:1-7. doi: 10.1016/j.bbi.2016.03.008. Epub 2016 Mar 11. Brain Behav Immun. 2017. PMID: 26975888 Review.

2

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system.

Chen J, Buchanan JB, Sparkman NL, Godbout JP, Freund GG, Johnson RW. Chen J, et al. Among authors: godbout jp. Brain Behav Immun. 2008 Mar;22(3):301-11. doi: 10.1016/j.bbi.2007.08.014. Epub 2007 Oct 24. Brain Behav Immun. 2008. PMID: 17951027 Free PMC article.

3

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.

Henry CJ, Huang Y, Wynne AM, Godbout JP. Henry CJ, et al. Among authors: godbout jp. Brain Behav Immun. 2009 Mar;23(3):309-17. doi: 10.1016/j.bbi.2008.09.002. Epub 2008 Sep 12. Brain Behav Immun. 2009. PMID: 18814846 Free PMC article.

4

Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge.

Wynne AM, Henry CJ, Huang Y, Cleland A, Godbout JP. Wynne AM, et al. Among authors: godbout jp. Brain Behav Immun. 2010 Oct;24(7):1190-201. doi: 10.1016/j.bbi.2010.05.011. Epub 2010 Jun 4. Brain Behav Immun. 2010. PMID: 20570721 Free PMC article.

5

Cognitive and behavioral consequences of impaired immunoregulation in aging.

Corona AW, Fenn AM, Godbout JP. Corona AW, et al. Among authors: godbout jp. J Neuroimmune Pharmacol. 2012 Mar;7(1):7-23. doi: 10.1007/s11481-011-9313-4. Epub 2011 Sep 20. J Neuroimmune Pharmacol. 2012. PMID: 21932047 Review.

6

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice.

Fenn AM, Henry CJ, Huang Y, Dugan A, Godbout JP. Fenn AM, et al. Among authors: godbout jp. Brain Behav Immun. 2012 Jul;26(5):766-77. doi: 10.1016/j.bbi.2011.10.003. Epub 2011 Oct 17. Brain Behav Immun. 2012. PMID: 22024136 Free PMC article.

7

Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice.

Corona AW, Norden DM, Skendelas JP, Huang Y, O'Connor JC, Lawson M, Dantzer R, Kelley KW, Godbout JP. Corona AW, et al. Among authors: godbout jp. Brain Behav Immun. 2013 Jul;31:134-42. doi: 10.1016/j.bbi.2012.08.008. Epub 2012 Aug 19. Brain Behav Immun. 2013. PMID: 22926082 Free PMC article.

8

Review: microglia of the aged brain: primed to be activated and resistant to regulation.

Norden DM, Godbout JP. Norden DM, et al. Among authors: godbout jp. Neuropathol Appl Neurobiol. 2013 Feb;39(1):19-34. doi: 10.1111/j.1365-2990.2012.01306.x. Neuropathol Appl Neurobiol. 2013. PMID: 23039106 Free PMC article. Review.

9

Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia.

Fenn AM, Gensel JC, Huang Y, Popovich PG, Lifshitz J, Godbout JP. Fenn AM, et al. Among authors: godbout jp. Biol Psychiatry. 2014 Oct 1;76(7):575-84. doi: 10.1016/j.biopsych.2013.10.014. Epub 2013 Oct 25. Biol Psychiatry. 2014. PMID: 24289885 Free PMC article.

10

IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury.

Fenn AM, Hall JC, Gensel JC, Popovich PG, Godbout JP. Fenn AM, et al. Among authors: godbout jp. J Neurosci. 2014 Jun 25;34(26):8904-17. doi: 10.1523/JNEUROSCI.1146-14.2014. J Neurosci. 2014. PMID: 24966389 Free PMC article.

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