Christianson DW - Search Results

1

General base-general acid catalysis by terpenoid cyclases.

Pemberton TA, Christianson DW. Pemberton TA, et al. Among authors: christianson dw. J Antibiot (Tokyo). 2016 Jul;69(7):486-93. doi: 10.1038/ja.2016.39. Epub 2016 Apr 13. J Antibiot (Tokyo). 2016. PMID: 27072285 Free PMC article. Review.

2

Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology.

Lesburg CA, Zhai G, Cane DE, Christianson DW. Lesburg CA, et al. Among authors: christianson dw. Science. 1997 Sep 19;277(5333):1820-4. doi: 10.1126/science.277.5333.1820. Science. 1997. PMID: 9295272

3

Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase.

Whittington DA, Wise ML, Urbansky M, Coates RM, Croteau RB, Christianson DW. Whittington DA, et al. Among authors: christianson dw. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15375-80. doi: 10.1073/pnas.232591099. Epub 2002 Nov 13. Proc Natl Acad Sci U S A. 2002. PMID: 12432096 Free PMC article.

4

Structural biology and chemistry of the terpenoid cyclases.

Christianson DW. Christianson DW. Chem Rev. 2006 Aug;106(8):3412-42. doi: 10.1021/cr050286w. Chem Rev. 2006. PMID: 16895335 Review. No abstract available.

5

X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.

Shishova EY, Di Costanzo L, Cane DE, Christianson DW. Shishova EY, et al. Among authors: christianson dw. Biochemistry. 2007 Feb 20;46(7):1941-51. doi: 10.1021/bi0622524. Epub 2007 Jan 30. Biochemistry. 2007. PMID: 17261032 Free PMC article.

6

Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates.

Aaron JA, Lin X, Cane DE, Christianson DW. Aaron JA, et al. Among authors: christianson dw. Biochemistry. 2010 Mar 2;49(8):1787-97. doi: 10.1021/bi902088z. Biochemistry. 2010. PMID: 20131801 Free PMC article.

7

Trinuclear Metal Clusters in Catalysis by Terpenoid Synthases.

Aaron JA, Christianson DW. Aaron JA, et al. Among authors: christianson dw. Pure Appl Chem. 2010;82(8):1585-1597. doi: 10.1351/PAC-CON-09-09-37. Pure Appl Chem. 2010. PMID: 21562622 Free PMC article.

8

Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase.

Li R, Chou WK, Himmelberger JA, Litwin KM, Harris GG, Cane DE, Christianson DW. Li R, et al. Among authors: christianson dw. Biochemistry. 2014 Feb 25;53(7):1155-68. doi: 10.1021/bi401643u. Epub 2014 Feb 11. Biochemistry. 2014. PMID: 24517311 Free PMC article.

9

Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.

Harris GG, Lombardi PM, Pemberton TA, Matsui T, Weiss TM, Cole KE, Köksal M, Murphy FV 4th, Vedula LS, Chou WK, Cane DE, Christianson DW. Harris GG, et al. Among authors: christianson dw. Biochemistry. 2015 Dec 8;54(48):7142-55. doi: 10.1021/acs.biochem.5b01143. Epub 2015 Nov 24. Biochemistry. 2015. PMID: 26598179 Free PMC article.

10

Multi-domain terpenoid cyclase architecture and prospects for proximity in bifunctional catalysis.

Chen M, Harris GG, Pemberton TA, Christianson DW. Chen M, et al. Among authors: christianson dw. Curr Opin Struct Biol. 2016 Dec;41:27-37. doi: 10.1016/j.sbi.2016.05.010. Epub 2016 Jun 7. Curr Opin Struct Biol. 2016. PMID: 27285057 Free PMC article. Review.

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