Zhuang W - Search Results

1

Determinants of Gefitinib toxicity in advanced non-small cell lung cancer (NSCLC): a pharmacogenomic study of metabolic enzymes and transporters.

Ma Y, Xin S, Huang M, Yang Y, Zhu C, Zhao H, Zhang Y, Chen L, Zhao Y, Li J, Zhuang W, Zhu X, Zhang L, Wang X. Ma Y, et al. Among authors: zhuang w. Pharmacogenomics J. 2017 Jul;17(4):325-330. doi: 10.1038/tpj.2016.31. Epub 2016 Apr 19. Pharmacogenomics J. 2017. PMID: 27089937

2

3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway.

Hou X, Bai X, Gou X, Zeng H, Xia C, Zhuang W, Chen X, Zhao Z, Huang M, Jin J. Hou X, et al. Among authors: zhuang w. Mol Cells. 2015 May;38(5):396-401. doi: 10.14348/molcells.2015.2183. Epub 2015 Mar 31. Mol Cells. 2015. PMID: 25843086 Free PMC article.

3

Simultaneous quantification of imatinib and its main metabolite N-demethyl-imatinib in human plasma by liquid chromatography-tandem mass spectrometry and its application to therapeutic drug monitoring in patients with gastrointestinal stromal tumor.

Zhuang W, Qiu HB, Chen XM, Yuan XH, Yang LF, Sun XW, Zhou XJ, Huang M, Wang XD, Zhou ZW. Zhuang W, et al. Biomed Chromatogr. 2017 Dec;31(12). doi: 10.1002/bmc.4022. Epub 2017 Aug 7. Biomed Chromatogr. 2017. PMID: 28621487

4

Imatinib-induced ophthalmological side-effects in GIST patients are associated with the variations of EGFR, SLC22A1, SLC22A5 and ABCB1.

Qiu HB, Zhuang W, Wu T, Xin S, Lin CZ, Ruan HL, Zhu X, Huang M, Li JL, Hou XY, Zhou ZW, Wang XD. Qiu HB, et al. Among authors: zhuang w. Pharmacogenomics J. 2018 May 22;18(3):460-466. doi: 10.1038/tpj.2017.40. Epub 2017 Aug 1. Pharmacogenomics J. 2018. PMID: 28762371

5

[Association between genetic polymorphisms and variation of imatinib pharmacokinetics in gastrointestinal stromal tumors].

Qiu H, Zhuang W, Wang X, Huang M, Zhou Z. Qiu H, et al. Among authors: zhuang w. Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Sep 25;20(9):1031-1034. Zhonghua Wei Chang Wai Ke Za Zhi. 2017. PMID: 28900995 Chinese.

6

Can therapeutic drug monitoring increase the safety of Imatinib in GIST patients?

Zhuang W, Xie JD, Zhou S, Zhou ZW, Zhou Y, Sun XW, Yuan XH, Huang M, Liu S, Xin S, Su QB, Qiu HB, Wang XD. Zhuang W, et al. Cancer Med. 2018 Feb;7(2):317-324. doi: 10.1002/cam4.1286. Epub 2018 Jan 7. Cancer Med. 2018. PMID: 29316372 Free PMC article.

7

Development and validation of a sensitive LC-MS/MS method for determination of gefitinib and its major metabolites in human plasma and its application in non-small cell lung cancer patients.

Guan S, Chen X, Wang F, Xin S, Feng W, Zhu X, Liu S, Zhuang W, Zhou S, Huang M, Wang X, Zhang L. Guan S, et al. Among authors: zhuang w. J Pharm Biomed Anal. 2019 Aug 5;172:364-371. doi: 10.1016/j.jpba.2019.03.060. Epub 2019 Mar 28. J Pharm Biomed Anal. 2019. PMID: 31096095

8

Polymorphisms of NF-κB pathway genes influence adverse drug reactions of gefitinib in NSCLC patients.

Xin S, Zhao Y, Wang C, Huang Y, Zhuang W, Ma Y, Huang M, Xu X, Wang X, Zhang L. Xin S, et al. Among authors: zhuang w. Pharmacogenomics J. 2020 Apr;20(2):285-293. doi: 10.1038/s41397-019-0115-z. Epub 2019 Oct 30. Pharmacogenomics J. 2020. PMID: 31664190

9

The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study.

Ma Y, Xin S, Lin Q, Zhuang W, Zhao Y, Zhu X, Zhao H, Huang M, Xun X, Yang Y, Fang W, Zhang L, Wang X. Ma Y, et al. Among authors: zhuang w. Ann Transl Med. 2019 Dec;7(24):806. doi: 10.21037/atm.2019.12.60. Ann Transl Med. 2019. PMID: 32042822 Free PMC article.

10

Establishment and application of a predictive model for gefitinib-induced severe rash based on pharmacometabolomic profiling and polymorphisms of transporters in non-small cell lung cancer.

Guan S, Chen X, Xin S, Liu S, Yang Y, Fang W, Huang Y, Zhao H, Zhu X, Zhuang W, Wang F, Feng W, Zhang X, Huang M, Wang X, Zhang L. Guan S, et al. Among authors: zhuang w. Transl Oncol. 2021 Jan;14(1):100951. doi: 10.1016/j.tranon.2020.100951. Epub 2020 Nov 19. Transl Oncol. 2021. PMID: 33221684 Free PMC article.

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