Hrstka SC - Search Results

1

Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model.

Wyles SP, Hrstka SC, Reyes S, Terzic A, Olson TM, Nelson TJ. Wyles SP, et al. Among authors: hrstka sc. Clin Transl Sci. 2016 Jun;9(3):158-67. doi: 10.1111/cts.12393. Epub 2016 Apr 22. Clin Transl Sci. 2016. PMID: 27105042 Free PMC article.

2

Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells.

Wyles SP, Li X, Hrstka SC, Reyes S, Oommen S, Beraldi R, Edwards J, Terzic A, Olson TM, Nelson TJ. Wyles SP, et al. Among authors: hrstka sc. Hum Mol Genet. 2016 Jan 15;25(2):254-65. doi: 10.1093/hmg/ddv468. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604136 Free PMC article.

3

NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis.

Hrstka SC, Li X, Nelson TJ; Wanek Program Genetics Pipeline Group. Hrstka SC, et al. Stem Cells. 2017 Apr;35(4):1106-1119. doi: 10.1002/stem.2582. Epub 2017 Mar 5. Stem Cells. 2017. PMID: 28142228

4

Quantification of Etoposide Hypersensitivity: A Sensitive, Functional Method for Assessing Pluripotent Stem Cell Quality.

Secreto FJ, Li X, Smith AJ, Bruinsma ES, Perales-Clemente E, Oommen S, Hawse G, Hrstka SCL, Arendt BK, Brandt EB, Wigle DA, Nelson TJ. Secreto FJ, et al. Among authors: hrstka scl. Stem Cells Transl Med. 2017 Oct;6(10):1829-1839. doi: 10.1002/sctm.17-0116. Epub 2017 Sep 19. Stem Cells Transl Med. 2017. PMID: 28924979 Free PMC article.

5

Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.

Folmes CD, Martinez-Fernandez A, Perales-Clemente E, Li X, McDonald A, Oglesbee D, Hrstka SC, Perez-Terzic C, Terzic A, Nelson TJ. Folmes CD, et al. Among authors: hrstka sc. Stem Cells. 2013 Jul;31(7):1298-308. doi: 10.1002/stem.1389. Stem Cells. 2013. PMID: 23553816 Free PMC article.

6

Compound heterozygous NOTCH1 mutations underlie impaired cardiogenesis in a patient with hypoplastic left heart syndrome.

Theis JL, Hrstka SC, Evans JM, O'Byrne MM, de Andrade M, O'Leary PW, Nelson TJ, Olson TM. Theis JL, et al. Among authors: hrstka sc. Hum Genet. 2015 Sep;134(9):1003-11. doi: 10.1007/s00439-015-1582-1. Epub 2015 Jul 12. Hum Genet. 2015. PMID: 26164125

7

Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with MYL2-R58Q-Mediated Apical Hypertrophic Cardiomyopathy Show Hypertrophy, Myofibrillar Disarray, and Calcium Perturbations.

Zhou W, Bos JM, Ye D, Tester DJ, Hrstka S, Maleszewski JJ, Ommen SR, Nishimura RA, Schaff HV, Kim CS, Ackerman MJ. Zhou W, et al. J Cardiovasc Transl Res. 2019 Oct;12(5):394-403. doi: 10.1007/s12265-019-09873-6. Epub 2019 Feb 22. J Cardiovasc Transl Res. 2019. PMID: 30796699

8

Proteomic analysis of human iPSC-derived sensory neurons implicates cell stress and microtubule dynamics dysfunction in bortezomib-induced peripheral neurotoxicity.

Hrstka SCL, Ankam S, Agac B, Klein JP, Moore RA, Narapureddy B, Schneider I, Hrstka RF, Dasari S, Staff NP. Hrstka SCL, et al. Exp Neurol. 2021 Jan;335:113520. doi: 10.1016/j.expneurol.2020.113520. Epub 2020 Oct 29. Exp Neurol. 2021. PMID: 33129842 Free PMC article.

9

Alterations of mesenchymal stromal cells in cerebrospinal fluid: insights from transcriptomics and an ALS clinical trial.

Krull AA, Setter DO, Gendron TF, Hrstka SCL, Polzin MJ, Hart J, Dudakovic A, Madigan NN, Dietz AB, Windebank AJ, van Wijnen AJ, Staff NP. Krull AA, et al. Among authors: hrstka scl. Stem Cell Res Ther. 2021 Mar 18;12(1):187. doi: 10.1186/s13287-021-02241-9. Stem Cell Res Ther. 2021. PMID: 33736701 Free PMC article.

10

Skin Extracellular Matrix Breakdown Following Paclitaxel Therapy in Patients with Chemotherapy-Induced Peripheral Neuropathy.

Staff NP, Hrstka SC, Dasari S, Capobianco E, Rieger S. Staff NP, et al. Among authors: hrstka sc. Cancers (Basel). 2023 Aug 21;15(16):4191. doi: 10.3390/cancers15164191. Cancers (Basel). 2023. PMID: 37627219 Free PMC article.

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