Isaacs K - Search Results

1

Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays.

Leonard JA, Sobel Leonard A, Chang DT, Edwards S, Lu J, Scholle S, Key P, Winter M, Isaacs K, Tan YM. Leonard JA, et al. Among authors: isaacs k. Environ Sci Technol. 2016 Jun 7;50(11):5961-71. doi: 10.1021/acs.est.6b00374. Epub 2016 May 12. Environ Sci Technol. 2016. PMID: 27124219 Free PMC article.

2

Development of a consumer product ingredient database for chemical exposure screening and prioritization.

Goldsmith MR, Grulke CM, Brooks RD, Transue TR, Tan YM, Frame A, Egeghy PP, Edwards R, Chang DT, Tornero-Velez R, Isaacs K, Wang A, Johnson J, Holm K, Reich M, Mitchell J, Vallero DA, Phillips L, Phillips M, Wambaugh JF, Judson RS, Buckley TJ, Dary CC. Goldsmith MR, et al. Among authors: isaacs k. Food Chem Toxicol. 2014 Mar;65:269-79. doi: 10.1016/j.fct.2013.12.029. Epub 2013 Dec 27. Food Chem Toxicol. 2014. PMID: 24374094

3

GPS-based microenvironment tracker (MicroTrac) model to estimate time-location of individuals for air pollution exposure assessments: model evaluation in central North Carolina.

Breen MS, Long TC, Schultz BD, Crooks J, Breen M, Langstaff JE, Isaacs KK, Tan YM, Williams RW, Cao Y, Geller AM, Devlin RB, Batterman SA, Buckley TJ. Breen MS, et al. Among authors: isaacs kk. J Expo Sci Environ Epidemiol. 2014 Jul;24(4):412-20. doi: 10.1038/jes.2014.13. Epub 2014 Mar 12. J Expo Sci Environ Epidemiol. 2014. PMID: 24619294 Free PMC article.

4

A new method for generating distributions of biomonitoring equivalents to support exposure assessment and prioritization.

Phillips MB, Sobus JR, George BJ, Isaacs K, Conolly R, Tan YM. Phillips MB, et al. Among authors: isaacs k. Regul Toxicol Pharmacol. 2014 Aug;69(3):434-42. doi: 10.1016/j.yrtph.2014.05.008. Epub 2014 May 17. Regul Toxicol Pharmacol. 2014. PMID: 24845241

5

SHEDS-HT: an integrated probabilistic exposure model for prioritizing exposures to chemicals with near-field and dietary sources.

Isaacs KK, Glen WG, Egeghy P, Goldsmith MR, Smith L, Vallero D, Brooks R, Grulke CM, Özkaynak H. Isaacs KK, et al. Environ Sci Technol. 2014 Nov 4;48(21):12750-9. doi: 10.1021/es502513w. Epub 2014 Oct 21. Environ Sci Technol. 2014. PMID: 25222184

6

Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.

Leonard JA, Tan YM, Gilbert M, Isaacs K, El-Masri H. Leonard JA, et al. Among authors: isaacs k. Toxicol Sci. 2016 May;151(1):57-70. doi: 10.1093/toxsci/kfw022. Epub 2016 Feb 10. Toxicol Sci. 2016. PMID: 26865668 Free PMC article.

7

Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards.

El-Masri H, Kleinstreuer N, Hines RN, Adams L, Tal T, Isaacs K, Wetmore BA, Tan YM. El-Masri H, et al. Among authors: isaacs k. Toxicol Sci. 2016 Jul;152(1):230-43. doi: 10.1093/toxsci/kfw082. Epub 2016 May 4. Toxicol Sci. 2016. PMID: 27208077 Free PMC article.

8

Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals.

Csiszar SA, Meyer DE, Dionisio KL, Egeghy P, Isaacs KK, Price PS, Scanlon KA, Tan YM, Thomas K, Vallero D, Bare JC. Csiszar SA, et al. Among authors: isaacs kk. Environ Sci Technol. 2016 Nov 1;50(21):11922-11934. doi: 10.1021/acs.est.6b02277. Epub 2016 Oct 18. Environ Sci Technol. 2016. PMID: 27668689 Free PMC article.

9

Characterizing the impact of projected changes in climate and air quality on human exposures to ozone.

Dionisio KL, Nolte CG, Spero TL, Graham S, Caraway N, Foley KM, Isaacs KK. Dionisio KL, et al. Among authors: isaacs kk. J Expo Sci Environ Epidemiol. 2017 May;27(3):260-270. doi: 10.1038/jes.2016.81. Epub 2017 Jan 25. J Expo Sci Environ Epidemiol. 2017. PMID: 28120830 Free PMC article.

10

Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates.

Moreau M, Leonard J, Phillips KA, Campbell J, Pendse SN, Nicolas C, Phillips M, Yoon M, Tan YM, Smith S, Pudukodu H, Isaacs K, Clewell H. Moreau M, et al. Among authors: isaacs k. Chemosphere. 2017 Oct;184:1194-1201. doi: 10.1016/j.chemosphere.2017.06.098. Epub 2017 Jun 24. Chemosphere. 2017. PMID: 28672700 Free PMC article.

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