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EZH2: biology, disease, and structure-based drug discovery.
Tan JZ, Yan Y, Wang XX, Jiang Y, Xu HE. Tan JZ, et al. Acta Pharmacol Sin. 2014 Feb;35(2):161-74. doi: 10.1038/aps.2013.161. Epub 2013 Dec 23. Acta Pharmacol Sin. 2014. PMID: 24362326 Free PMC article. Review.
Structure of the PRC2 complex and application to drug discovery.
Shi Y, Wang XX, Zhuang YW, Jiang Y, Melcher K, Xu HE. Shi Y, et al. Acta Pharmacol Sin. 2017 Jul;38(7):963-976. doi: 10.1038/aps.2017.7. Epub 2017 Apr 17. Acta Pharmacol Sin. 2017. PMID: 28414199 Free PMC article. Review.
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist.
Yin W, Zhou XE, Yang D, de Waal PW, Wang M, Dai A, Cai X, Huang CY, Liu P, Wang X, Yin Y, Liu B, Zhou Y, Wang J, Liu H, Caffrey M, Melcher K, Xu Y, Wang MW, Xu HE, Jiang Y. Yin W, et al. Among authors: wang x, wang j, wang m, wang mw. Cell Discov. 2018 Mar 13;4:12. doi: 10.1038/s41421-018-0009-2. eCollection 2018. Cell Discov. 2018. PMID: 29560272 Free PMC article.
A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H. Yin W, et al. Among authors: wang x. Cell Res. 2019 Dec;29(12):971-983. doi: 10.1038/s41422-019-0256-2. Epub 2019 Nov 27. Cell Res. 2019. PMID: 31776446 Free PMC article.
Molecular mechanisms of fentanyl mediated β-arrestin biased signaling.
de Waal PW, Shi J, You E, Wang X, Melcher K, Jiang Y, Xu HE, Dickson BM. de Waal PW, et al. Among authors: wang x. PLoS Comput Biol. 2020 Apr 10;16(4):e1007394. doi: 10.1371/journal.pcbi.1007394. eCollection 2020 Apr. PLoS Comput Biol. 2020. PMID: 32275713 Free PMC article.
Structural insights into the activation of GLP-1R by a small molecule agonist.
Ma H, Huang W, Wang X, Zhao L, Jiang Y, Liu F, Guo W, Sun X, Zhong W, Yuan D, Xu HE. Ma H, et al. Among authors: wang x. Cell Res. 2020 Dec;30(12):1140-1142. doi: 10.1038/s41422-020-0384-8. Epub 2020 Jul 28. Cell Res. 2020. PMID: 32724086 Free PMC article. No abstract available.
206,310 results
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