Xu K - Search Results

1

A Radiotracer Strategy to Quantify PARP-1 Expression In Vivo Provides a Biomarker That Can Enable Patient Selection for PARP Inhibitor Therapy.

Makvandi M, Xu K, Lieberman BP, Anderson RC, Effron SS, Winters HD, Zeng C, McDonald ES, Pryma DA, Greenberg RA, Mach RH. Makvandi M, et al. Among authors: xu k. Cancer Res. 2016 Aug 1;76(15):4516-24. doi: 10.1158/0008-5472.CAN-16-0416. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261505 Free PMC article.

2

The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer.

Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA, Mach RH. Makvandi M, et al. Among authors: xu k. Biochem Biophys Res Commun. 2015 Nov 27;467(4):1070-5. doi: 10.1016/j.bbrc.2015.09.157. Epub 2015 Oct 9. Biochem Biophys Res Commun. 2015. PMID: 26453012 Free PMC article.

3

[(18)F]FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer.

Edmonds CE, Makvandi M, Lieberman BP, Xu K, Zeng C, Li S, Hou C, Lee H, Greenberg RA, Mankoff DA, Mach RH. Edmonds CE, et al. Among authors: xu k. Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):94-101. eCollection 2016. Am J Nucl Med Mol Imaging. 2016. PMID: 27069769 Free PMC article.

4

Iodinated benzimidazole PARP radiotracer for evaluating PARP1/2 expression in vitro and in vivo.

Anderson RC, Makvandi M, Xu K, Lieberman BP, Zeng C, Pryma DA, Mach RH. Anderson RC, et al. Among authors: xu k. Nucl Med Biol. 2016 Dec;43(12):752-758. doi: 10.1016/j.nucmedbio.2016.08.007. Epub 2016 Aug 12. Nucl Med Biol. 2016. PMID: 27689533

5

PARP-1 Expression Quantified by [¹⁸F]FluorThanatrace: A Biomarker of Response to PARP Inhibition Adjuvant to Radiation Therapy.

Sander Effron S, Makvandi M, Lin L, Xu K, Li S, Lee H, Hou C, Pryma DA, Koch C, Mach RH. Sander Effron S, et al. Among authors: xu k. Cancer Biother Radiopharm. 2017 Feb;32(1):9-15. doi: 10.1089/cbr.2016.2133. Epub 2017 Jan 24. Cancer Biother Radiopharm. 2017. PMID: 28118040 Free PMC article.

6

Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation.

Hou C, Hsieh CJ, Li S, Lee H, Graham TJ, Xu K, Weng CC, Doot RK, Chu W, Chakraborty SK, Dugan LL, Mintun MA, Mach RH. Hou C, et al. Among authors: xu k. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586. doi: 10.1021/acschemneuro.7b00385. Epub 2017 Dec 3. ACS Chem Neurosci. 2018. PMID: 29099578 Free PMC article.

7

Highly Selective Dopamine D₃ Receptor Antagonists with Arylated Diazaspiro Alkane Cores.

Reilly SW, Griffin S, Taylor M, Sahlholm K, Weng CC, Xu K, Jacome DA, Luedtke RR, Mach RH. Reilly SW, et al. Among authors: xu k. J Med Chem. 2017 Dec 14;60(23):9905-9910. doi: 10.1021/acs.jmedchem.7b01248. Epub 2017 Nov 21. J Med Chem. 2017. PMID: 29125762 Free PMC article.

8

A PET imaging agent for evaluating PARP-1 expression in ovarian cancer.

Makvandi M, Pantel A, Schwartz L, Schubert E, Xu K, Hsieh CJ, Hou C, Kim H, Weng CC, Winters H, Doot R, Farwell MD, Pryma DA, Greenberg RA, Mankoff DA, Simpkins F, Mach RH, Lin LL. Makvandi M, et al. Among authors: xu k. J Clin Invest. 2018 May 1;128(5):2116-2126. doi: 10.1172/JCI97992. Epub 2018 Apr 16. J Clin Invest. 2018. PMID: 29509546 Free PMC article. Clinical Trial.

9

Rapid Cu-Catalyzed [²¹¹At]Astatination and [¹²⁵I]Iodination of Boronic Esters at Room Temperature.

Reilly SW, Makvandi M, Xu K, Mach RH. Reilly SW, et al. Among authors: xu k. Org Lett. 2018 Apr 6;20(7):1752-1755. doi: 10.1021/acs.orglett.8b00232. Epub 2018 Mar 21. Org Lett. 2018. PMID: 29561158 Free PMC article.

10

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules.

Hsieh CJ, Ferrie JJ, Xu K, Lee I, Graham TJA, Tu Z, Yu J, Dhavale D, Kotzbauer P, Petersson EJ, Mach RH. Hsieh CJ, et al. Among authors: xu k. ACS Chem Neurosci. 2018 Nov 21;9(11):2521-2527. doi: 10.1021/acschemneuro.8b00177. Epub 2018 May 16. ACS Chem Neurosci. 2018. PMID: 29750499 Free PMC article.

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