Lu JB - Search Results

1

Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers.

Abdelhady AM, Shugg T, Thong N, Lu JB, Kreutz Y, Jaynes HA, Robarge JD, Tisdale JE, Desta Z, Overholser BR. Abdelhady AM, et al. Among authors: lu jb. J Cardiovasc Electrophysiol. 2016 Oct;27(10):1206-1213. doi: 10.1111/jce.13032. Epub 2016 Jul 25. J Cardiovasc Electrophysiol. 2016. PMID: 27333947 Free PMC article. Clinical Trial.

2

Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.

Masters AR, Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z. Masters AR, et al. Among authors: lu jb. J Pharmacol Exp Ther. 2016 Aug;358(2):230-8. doi: 10.1124/jpet.116.232876. Epub 2016 Jun 2. J Pharmacol Exp Ther. 2016. PMID: 27255113 Free PMC article. Clinical Trial.

3

Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.

Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z. Gufford BT, et al. Among authors: lu jb. Drug Metab Dispos. 2016 Apr;44(4):544-53. doi: 10.1124/dmd.115.068908. Epub 2016 Jan 22. Drug Metab Dispos. 2016. PMID: 26802129 Free PMC article. Clinical Trial.

4

Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.

Liu SN, Lu JBL, Watson CJW, Lazarus P, Desta Z, Gufford BT. Liu SN, et al. Drug Metab Dispos. 2019 May;47(5):535-544. doi: 10.1124/dmd.118.085035. Epub 2019 Feb 25. Drug Metab Dispos. 2019. PMID: 30804050 Free PMC article.

5

Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers.

Gufford BT, Metzger IF, Bamfo NO, Benson EA, Masters AR, Lu JBL, Desta Z. Gufford BT, et al. J Pharmacol Exp Ther. 2022 Jul 7;382(3):313-26. doi: 10.1124/jpet.122.001277. Online ahead of print. J Pharmacol Exp Ther. 2022. PMID: 35798386 Free PMC article.

6

Stereoselective Metabolism of Bupropion to Active Metabolites in Cellular Fractions of Human Liver and Intestine.

Bamfo NO, Lu JB, Desta Z. Bamfo NO, et al. Among authors: lu jb. Drug Metab Dispos. 2023 Jan;51(1):54-66. doi: 10.1124/dmd.122.000867. Epub 2022 May 5. Drug Metab Dispos. 2023. PMID: 35512805 Free PMC article.

7

Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Preexposure Prophylaxis.

Liu SN, Gufford BT, Lu JBL, Bushman LR, Anderson PL, Bergstrom RF, Desta Z, Gupta SK. Liu SN, et al. Clin Pharmacol Ther. 2020 May;107(5):1200-1208. doi: 10.1002/cpt.1714. Epub 2019 Dec 31. Clin Pharmacol Ther. 2020. PMID: 31675437 Free PMC article. Clinical Trial.

8

In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases.

Cardoso Jde O, Oliveira RV, Lu JB, Desta Z. Cardoso Jde O, et al. Among authors: lu jb. Drug Metab Dispos. 2015 Dec;43(12):1905-16. doi: 10.1124/dmd.115.065763. Drug Metab Dispos. 2015. PMID: 26374173 Free PMC article.

9

The Cytochrome P450 Enzyme Responsible for the Production of (Z)-Norendoxifen in vitro.

Ma J, Chu Z, Lu JBL, Liu J, Zhang Q, Liu Z, Tang D. Ma J, et al. Chem Biodivers. 2018 Jan;15(1). doi: 10.1002/cbdv.201700287. Epub 2017 Dec 28. Chem Biodivers. 2018. PMID: 28834279

10

Rapid intracellular acidification is a plant defense response countered by the brown planthopper.

Jiang Y, Zhang XY, Li S, Xie YC, Luo XM, Yang Y, Pu Z, Zhang L, Lu JB, Huang HJ, Zhang CX, He SY. Jiang Y, et al. Among authors: lu jb. Curr Biol. 2024 Oct 14:S0960-9822(24)01280-6. doi: 10.1016/j.cub.2024.09.039. Online ahead of print. Curr Biol. 2024. PMID: 39406243 Free article.

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