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12(S)-HETE increases intracellular Ca(2+) in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply.
Nguyen CH, Brenner S, Huttary N, Li Y, Atanasov AG, Dirsch VM, Holzner S, Stadler S, Riha J, Krieger S, Milovanovic D, Fristiohardy A, Simonitsch-Klupp I, Dolznig H, Saiko P, Szekeres T, Giessrigl B, Jäger W, Krupitza G. Nguyen CH, et al. Among authors: li y. Cancer Lett. 2016 Sep 28;380(1):174-83. doi: 10.1016/j.canlet.2016.06.022. Epub 2016 Jul 4. Cancer Lett. 2016. PMID: 27390016
Anti-leukemia efficacy of the dual BCL2/BCL-XL inhibitor AZD0466 in acute lymphoblastic leukemia preclinical models.
Kannan S, Li Y, Baran N, Yang X, Ghotbaldini S, Tatarata QZ, Yoshimura S, Li Z, Hsiao YC, Balachander SB, Andersen CL, Cidado J, Yu J, Jain N, Yang JJ, Konopleva MY. Kannan S, et al. Among authors: li y. Blood Adv. 2024 Nov 19:bloodadvances.2024013423. doi: 10.1182/bloodadvances.2024013423. Online ahead of print. Blood Adv. 2024. PMID: 39561378
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