Othman AA - Search Results

1

Efficacy and Safety of ABT-494, a Selective JAK-1 Inhibitor, in a Phase IIb Study in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate.

Genovese MC, Smolen JS, Weinblatt ME, Burmester GR, Meerwein S, Camp HS, Wang L, Othman AA, Khan N, Pangan AL, Jungerwirth S. Genovese MC, et al. Among authors: othman aa. Arthritis Rheumatol. 2016 Dec;68(12):2857-2866. doi: 10.1002/art.39808. Arthritis Rheumatol. 2016. PMID: 27390150 Free PMC article. Clinical Trial.

2

A randomized trial of the efficacy and safety of the H3 antagonist ABT-288 in cognitive impairment associated with schizophrenia.

Haig GM, Bain E, Robieson W, Othman AA, Baker J, Lenz RA. Haig GM, et al. Among authors: othman aa. Schizophr Bull. 2014 Nov;40(6):1433-42. doi: 10.1093/schbul/sbt240. Epub 2014 Feb 10. Schizophr Bull. 2014. PMID: 24516190 Free PMC article. Clinical Trial.

3

A randomized study of H3 antagonist ABT-288 in mild-to-moderate Alzheimer's dementia.

Haig GM, Pritchett Y, Meier A, Othman AA, Hall C, Gault LM, Lenz RA. Haig GM, et al. Among authors: othman aa. J Alzheimers Dis. 2014;42(3):959-71. doi: 10.3233/JAD-140291. J Alzheimers Dis. 2014. PMID: 25024314 Free article. Clinical Trial.

4

A Randomized Trial to Assess the Efficacy and Safety of ABT-126, a Selective α7 Nicotinic Acetylcholine Receptor Agonist, in the Treatment of Cognitive Impairment in Schizophrenia.

Haig GM, Bain EE, Robieson WZ, Baker JD, Othman AA. Haig GM, et al. Among authors: othman aa. Am J Psychiatry. 2016 Aug 1;173(8):827-35. doi: 10.1176/appi.ajp.2015.15010093. Epub 2016 Mar 4. Am J Psychiatry. 2016. PMID: 26940805 Clinical Trial.

5

Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis.

Mohamed MF, Camp HS, Jiang P, Padley RJ, Asatryan A, Othman AA. Mohamed MF, et al. Among authors: othman aa. Clin Pharmacokinet. 2016 Dec;55(12):1547-1558. doi: 10.1007/s40262-016-0419-y. Clin Pharmacokinet. 2016. PMID: 27272171 Clinical Trial.

6

The α7 Nicotinic Agonist ABT-126 in the Treatment of Cognitive Impairment Associated with Schizophrenia in Nonsmokers: Results from a Randomized Controlled Phase 2b Study.

Haig G, Wang D, Othman AA, Zhao J. Haig G, et al. Among authors: othman aa. Neuropsychopharmacology. 2016 Nov;41(12):2893-2902. doi: 10.1038/npp.2016.101. Epub 2016 Jun 20. Neuropsychopharmacology. 2016. PMID: 27319970 Free PMC article. Clinical Trial.

7

A Phase IIb Study of ABT-494, a Selective JAK-1 Inhibitor, in Patients With Rheumatoid Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Therapy.

Kremer JM, Emery P, Camp HS, Friedman A, Wang L, Othman AA, Khan N, Pangan AL, Jungerwirth S, Keystone EC. Kremer JM, et al. Among authors: othman aa. Arthritis Rheumatol. 2016 Dec;68(12):2867-2877. doi: 10.1002/art.39801. Arthritis Rheumatol. 2016. PMID: 27389975 Free PMC article. Clinical Trial.

8

Assessment of effect of CYP3A inhibition, CYP induction, OATP1B inhibition, and high-fat meal on pharmacokinetics of the JAK1 inhibitor upadacitinib.

Mohamed MF, Jungerwirth S, Asatryan A, Jiang P, Othman AA. Mohamed MF, et al. Among authors: othman aa. Br J Clin Pharmacol. 2017 Oct;83(10):2242-2248. doi: 10.1111/bcp.13329. Epub 2017 Jun 19. Br J Clin Pharmacol. 2017. PMID: 28503781 Free PMC article. Clinical Trial.

9

Pharmacokinetics of ABT-122, a TNF-α- and IL-17A-Targeted Dual-Variable Domain Immunoglobulin, in Healthy Subjects and Patients with Rheumatoid Arthritis: Results from Three Phase I Trials.

Khatri A, Goss S, Jiang P, Mansikka H, Othman AA. Khatri A, et al. Among authors: othman aa. Clin Pharmacokinet. 2018 May;57(5):613-623. doi: 10.1007/s40262-017-0580-y. Clin Pharmacokinet. 2018. PMID: 28744796 Clinical Trial.

10

Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia: Results From a Phase 2b Randomized Controlled Study in Smokers.

Haig GM, Wang D, Zhao J, Othman AA, Bain EE. Haig GM, et al. Among authors: othman aa. J Clin Psychiatry. 2018 May/Jun;79(3):16m11162. doi: 10.4088/JCP.16m11162. J Clin Psychiatry. 2018. PMID: 28922590 Clinical Trial.

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