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Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.
Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW. Moon SH, et al. Among authors: abendschein d. J Biol Chem. 2016 Sep 9;291(37):19687-700. doi: 10.1074/jbc.M116.740597. Epub 2016 Jul 23. J Biol Chem. 2016. PMID: 27453526 Free PMC article.
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW. Mancuso DJ, et al. J Biol Chem. 2007 Mar 23;282(12):9216-27. doi: 10.1074/jbc.M607307200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213206 Free article.
Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine.
Dietrich HH, Abendschein DR, Moon SH, Nayeb-Hashemi N, Mancuso DJ, Jenkins CM, Kaltenbronn KM, Blumer KJ, Turk J, Gross RW. Dietrich HH, et al. Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2208-20. doi: 10.1152/ajpheart.00839.2009. Epub 2010 Apr 9. Am J Physiol Heart Circ Physiol. 2010. PMID: 20382858 Free PMC article.
122 results