Leeper DB - Search Results

1

Mechanism of antineoplastic activity of lonidamine.

Nath K, Guo L, Nancolas B, Nelson DS, Shestov AA, Lee SC, Roman J, Zhou R, Leeper DB, Halestrap AP, Blair IA, Glickson JD. Nath K, et al. Among authors: leeper db. Biochim Biophys Acta. 2016 Dec;1866(2):151-162. doi: 10.1016/j.bbcan.2016.08.001. Epub 2016 Aug 4. Biochim Biophys Acta. 2016. PMID: 27497601 Free PMC article. Review.

2

(31) P and (1) H MRS of DB-1 melanoma xenografts: lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan.

Nath K, Nelson DS, Ho AM, Lee SC, Darpolor MM, Pickup S, Zhou R, Heitjan DF, Leeper DB, Glickson JD. Nath K, et al. Among authors: leeper db. NMR Biomed. 2013 Jan;26(1):98-105. doi: 10.1002/nbm.2824. Epub 2012 Jun 29. NMR Biomed. 2013. PMID: 22745015 Free PMC article.

3

Lonidamine induces intracellular tumor acidification and ATP depletion in breast, prostate and ovarian cancer xenografts and potentiates response to doxorubicin.

Nath K, Nelson DS, Heitjan DF, Leeper DB, Zhou R, Glickson JD. Nath K, et al. Among authors: leeper db. NMR Biomed. 2015 Mar;28(3):281-90. doi: 10.1002/nbm.3240. Epub 2014 Dec 12. NMR Biomed. 2015. PMID: 25504852 Free PMC article.

4

Effects of hyperglycemia on lonidamine-induced acidification and de-energization of human melanoma xenografts and sensitization to melphalan.

Nath K, Nelson DS, Heitjan DF, Zhou R, Leeper DB, Glickson JD. Nath K, et al. Among authors: leeper db. NMR Biomed. 2015 Mar;28(3):395-403. doi: 10.1002/nbm.3260. NMR Biomed. 2015. PMID: 25702942 Free PMC article.

5

Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine.

Guo L, Shestov AA, Worth AJ, Nath K, Nelson DS, Leeper DB, Glickson JD, Blair IA. Guo L, et al. Among authors: leeper db. J Biol Chem. 2016 Jan 1;291(1):42-57. doi: 10.1074/jbc.M115.697516. Epub 2015 Oct 31. J Biol Chem. 2016. PMID: 26521302 Free PMC article.

6

The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.

Nancolas B, Guo L, Zhou R, Nath K, Nelson DS, Leeper DB, Blair IA, Glickson JD, Halestrap AP. Nancolas B, et al. Among authors: leeper db. Biochem J. 2016 Apr 1;473(7):929-36. doi: 10.1042/BJ20151120. Epub 2016 Feb 1. Biochem J. 2016. PMID: 26831515 Free PMC article.

7

Effect of Lonidamine on Systemic Therapy of DB-1 Human Melanoma Xenografts with Temozolomide.

Nath K, Nelson DS, Roman J, Putt ME, Lee SC, Leeper DB, Glickson JD. Nath K, et al. Among authors: leeper db. Anticancer Res. 2017 Jul;37(7):3413-3421. doi: 10.21873/anticanres.11708. Anticancer Res. 2017. PMID: 28668829 Free PMC article.

8

Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin.

Nath K, Roman J, Nelson DS, Guo L, Lee SC, Orlovskiy S, Muriuki K, Heitjan DF, Pickup S, Leeper DB, Blair IA, Putt ME, Glickson JD. Nath K, et al. Among authors: leeper db. Sci Rep. 2018 Oct 2;8(1):14654. doi: 10.1038/s41598-018-33019-4. Sci Rep. 2018. PMID: 30279592 Free PMC article.

9

Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells.

Shestov AA, Mancuso A, Lee SC, Guo L, Nelson DS, Roman JC, Henry PG, Leeper DB, Blair IA, Glickson JD. Shestov AA, et al. Among authors: leeper db. J Biol Chem. 2016 Mar 4;291(10):5157-71. doi: 10.1074/jbc.M115.701862. Epub 2015 Dec 24. J Biol Chem. 2016. PMID: 26703469 Free PMC article.

10

Comparison of the Lonidamine Potentiated Effect of Nitrogen Mustard Alkylating Agents on the Systemic Treatment of DB-1 Human Melanoma Xenografts in Mice.

Nath K, Nelson DS, Putt ME, Leeper DB, Garman B, Nathanson KL, Glickson JD. Nath K, et al. Among authors: leeper db. PLoS One. 2016 Jun 10;11(6):e0157125. doi: 10.1371/journal.pone.0157125. eCollection 2016. PLoS One. 2016. PMID: 27285585 Free PMC article.

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