Shan Q - Search Results

1

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.

Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, Ahmed R. Im SJ, et al. Among authors: shan q. Nature. 2016 Sep 15;537(7620):417-421. doi: 10.1038/nature19330. Epub 2016 Aug 2. Nature. 2016. PMID: 27501248 Free PMC article.

2

Peripherally induced brain tissue-resident memory CD8⁺ T cells mediate protection against CNS infection.

Urban SL, Jensen IJ, Shan Q, Pewe LL, Xue HH, Badovinac VP, Harty JT. Urban SL, et al. Among authors: shan q. Nat Immunol. 2020 Aug;21(8):938-949. doi: 10.1038/s41590-020-0711-8. Epub 2020 Jun 22. Nat Immunol. 2020. PMID: 32572242 Free PMC article.

3

Tcf1 preprograms the mobilization of glycolysis in central memory CD8⁺ T cells during recall responses.

Shan Q, Hu SS, Zhu S, Chen X, Badovinac VP, Peng W, Zang C, Xue HH. Shan Q, et al. Nat Immunol. 2022 Mar;23(3):386-398. doi: 10.1038/s41590-022-01131-3. Epub 2022 Feb 21. Nat Immunol. 2022. PMID: 35190717 Free PMC article.

4

LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

Choi YS, Gullicksrud JA, Xing S, Zeng Z, Shan Q, Li F, Love PE, Peng W, Xue HH, Crotty S. Choi YS, et al. Among authors: shan q. Nat Immunol. 2015 Sep;16(9):980-90. doi: 10.1038/ni.3226. Epub 2015 Jul 27. Nat Immunol. 2015. PMID: 26214741 Free PMC article.

5

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.

Martin MD, Kim MT, Shan Q, Sompallae R, Xue HH, Harty JT, Badovinac VP. Martin MD, et al. Among authors: shan q. PLoS Pathog. 2015 Oct 20;11(10):e1005219. doi: 10.1371/journal.ppat.1005219. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485703 Free PMC article.

6

Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.

Xing S, Li F, Zeng Z, Zhao Y, Yu S, Shan Q, Li Y, Phillips FC, Maina PK, Qi HH, Liu C, Zhu J, Pope RM, Musselman CA, Zeng C, Peng W, Xue HH. Xing S, et al. Among authors: shan q. Nat Immunol. 2016 Jun;17(6):695-703. doi: 10.1038/ni.3456. Epub 2016 Apr 25. Nat Immunol. 2016. PMID: 27111144 Free PMC article.

7

The transcription factor Runx3 guards cytotoxic CD8⁺ effector T cells against deviation towards follicular helper T cell lineage.

Shan Q, Zeng Z, Xing S, Li F, Hartwig SM, Gullicksrud JA, Kurup SP, Van Braeckel-Budimir N, Su Y, Martin MD, Varga SM, Taniuchi I, Harty JT, Peng W, Badovinac VP, Xue HH. Shan Q, et al. Nat Immunol. 2017 Aug;18(8):931-939. doi: 10.1038/ni.3773. Epub 2017 Jun 12. Nat Immunol. 2017. PMID: 28604718 Free PMC article.

8

Ezh2 programs T_FH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf.

Li F, Zeng Z, Xing S, Gullicksrud JA, Shan Q, Choi J, Badovinac VP, Crotty S, Peng W, Xue HH. Li F, et al. Among authors: shan q. Nat Commun. 2018 Dec 21;9(1):5452. doi: 10.1038/s41467-018-07853-z. Nat Commun. 2018. PMID: 30575739 Free PMC article.

9

Ectopic Tcf1 expression instills a stem-like program in exhausted CD8⁺ T cells to enhance viral and tumor immunity.

Shan Q, Hu S, Chen X, Danahy DB, Badovinac VP, Zang C, Xue HH. Shan Q, et al. Cell Mol Immunol. 2021 May;18(5):1262-1277. doi: 10.1038/s41423-020-0436-5. Epub 2020 Apr 27. Cell Mol Immunol. 2021. PMID: 32341523 Free PMC article.

10

TCF1 in T cell immunity: a broadened frontier.

Zhao X, Shan Q, Xue HH. Zhao X, et al. Among authors: shan q. Nat Rev Immunol. 2022 Mar;22(3):147-157. doi: 10.1038/s41577-021-00563-6. Epub 2021 Jun 14. Nat Rev Immunol. 2022. PMID: 34127847 Review.

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