Prestwich GD - Search Results

1

TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.

Ryskamp DA, Frye AM, Phuong TT, Yarishkin O, Jo AO, Xu Y, Lakk M, Iuso A, Redmon SN, Ambati B, Hageman G, Prestwich GD, Torrejon KY, Križaj D. Ryskamp DA, et al. Among authors: prestwich gd. Sci Rep. 2016 Aug 11;6:30583. doi: 10.1038/srep30583. Sci Rep. 2016. PMID: 27510430 Free PMC article.

2

Synthesis of chiral (alpha,alpha-difluoroalkyl)phosphonate analogues of (lyso)phosphatidic acid via hydrolytic kinetic resolution.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Org Lett. 2002 Nov 14;4(23):4021-4. doi: 10.1021/ol026684s. Org Lett. 2002. PMID: 12423076

3

Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acid.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2002 Oct 4;67(20):7158-61. doi: 10.1021/jo0203037. J Org Chem. 2002. PMID: 12354017

4

Synthesis of monofluorinated analogues of lysophosphatidic acid.

Xu Y, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2003 Jun 27;68(13):5320-30. doi: 10.1021/jo020729l. J Org Chem. 2003. PMID: 12816494

5

Practical enantiospecific syntheses of lysobisphosphatidic acid and its analogues.

Jiang G, Xu Y, Prestwich GD. Jiang G, et al. Among authors: prestwich gd. J Org Chem. 2006 Feb 3;71(3):934-9. doi: 10.1021/jo051894e. J Org Chem. 2006. PMID: 16438504

6

Synthesis of alpha-fluorinated phosphonates from alpha-fluorovinylphosphonates: a new route to analogues of lysophosphatidic acid.

Xu Y, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Org Lett. 2003 Jun 26;5(13):2267-70. doi: 10.1021/ol034597+. Org Lett. 2003. PMID: 12816425

7

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid.

Xu Y, Fang Y, Chen J, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1461-4. doi: 10.1016/j.bmcl.2004.01.020. Bioorg Med Chem Lett. 2004. PMID: 15006382

8

Synthesis and biological activity of phospholipase C-resistant analogues of phosphatidylinositol 4,5-bisphosphate.

Zhang H, Xu Y, Zhang Z, Liman ER, Prestwich GD. Zhang H, et al. Among authors: prestwich gd. J Am Chem Soc. 2006 May 3;128(17):5642-3. doi: 10.1021/ja060621d. J Am Chem Soc. 2006. PMID: 16637624 Free PMC article.

9

Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.

Xu Y, Tanaka M, Arai H, Aoki J, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5323-8. doi: 10.1016/j.bmcl.2004.08.019. Bioorg Med Chem Lett. 2004. PMID: 15454220

10

Synthesis and molecular recognition of phosphatidylinositol-3-methylenephosphate.

Gajewiak J, Xu Y, Lee SA, Kutateladze TG, Prestwich GD. Gajewiak J, et al. Among authors: prestwich gd. Org Lett. 2006 Jun 22;8(13):2811-3. doi: 10.1021/ol060903i. Org Lett. 2006. PMID: 16774263 Free PMC article.

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