Houde VP - Search Results

1

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1.

Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR. Smith BK, et al. Among authors: houde vp. Diabetes. 2016 Nov;65(11):3352-3361. doi: 10.2337/db16-0564. Epub 2016 Aug 23. Diabetes. 2016. PMID: 27554471 Free PMC article.

2

Multi-Omics Data Integration Reveals Key Variables Contributing to Subgingival Microbiome Dysbiosis-Induced Inflammatory Response in a Hyperglycemic Microenvironment.

Lafleur S, Bodein A, Mbuya Malaïka Mutombo J, Mathieu A, Joly Beauparlant C, Minne X, Chandad F, Droit A, Houde VP. Lafleur S, et al. Among authors: houde vp. Int J Mol Sci. 2023 May 16;24(10):8832. doi: 10.3390/ijms24108832. Int J Mol Sci. 2023. PMID: 37240180 Free PMC article.

3

Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.

O'Brien AJ, Villani LA, Broadfield LA, Houde VP, Galic S, Blandino G, Kemp BE, Tsakiridis T, Muti P, Steinberg GR. O'Brien AJ, et al. Among authors: houde vp. Biochem J. 2015 Jul 15;469(2):177-87. doi: 10.1042/BJ20150122. Epub 2015 May 5. Biochem J. 2015. PMID: 25940306

4

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration.

Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR. Villani LA, et al. Among authors: houde vp. Mol Metab. 2016 Aug 26;5(10):1048-1056. doi: 10.1016/j.molmet.2016.08.014. eCollection 2016 Oct. Mol Metab. 2016. PMID: 27689018 Free PMC article.

5

AMPK β1 reduces tumor progression and improves survival in p53 null mice.

Houde VP, Donzelli S, Sacconi A, Galic S, Hammill JA, Bramson JL, Foster RA, Tsakiridis T, Kemp BE, Grasso G, Blandino G, Muti P, Steinberg GR. Houde VP, et al. Mol Oncol. 2017 Sep;11(9):1143-1155. doi: 10.1002/1878-0261.12079. Epub 2017 Jun 28. Mol Oncol. 2017. PMID: 28544264 Free PMC article.

6

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.

Lally JSV, Ghoshal S, DePeralta DK, Moaven O, Wei L, Masia R, Erstad DJ, Fujiwara N, Leong V, Houde VP, Anagnostopoulos AE, Wang A, Broadfield LA, Ford RJ, Foster RA, Bates J, Sun H, Wang T, Liu H, Ray AS, Saha AK, Greenwood J, Bhat S, Harriman G, Miao W, Rocnik JL, Westlin WF, Muti P, Tsakiridis T, Harwood HJ Jr, Kapeller R, Hoshida Y, Tanabe KK, Steinberg GR, Fuchs BC. Lally JSV, et al. Among authors: houde vp. Cell Metab. 2019 Jan 8;29(1):174-182.e5. doi: 10.1016/j.cmet.2018.08.020. Epub 2018 Sep 20. Cell Metab. 2019. PMID: 30244972 Free PMC article.

7

Salsalate reduces atherosclerosis through AMPKβ1 in mice.

Day EA, Ford RJ, Smith BK, Houde VP, Stypa S, Rehal S, Lhotak S, Kemp BE, Trigatti BL, Werstuck GH, Austin RC, Fullerton MD, Steinberg GR. Day EA, et al. Among authors: houde vp. Mol Metab. 2021 Nov;53:101321. doi: 10.1016/j.molmet.2021.101321. Epub 2021 Aug 21. Mol Metab. 2021. PMID: 34425254 Free PMC article.

8

Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.

Houde VP, Brûlé S, Festuccia WT, Blanchard PG, Bellmann K, Deshaies Y, Marette A. Houde VP, et al. Diabetes. 2010 Jun;59(6):1338-48. doi: 10.2337/db09-1324. Epub 2010 Mar 18. Diabetes. 2010. PMID: 20299475 Free PMC article.

9

Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells.

Shum M, Houde VP, Bellemare V, Junges Moreira R, Bellmann K, St-Pierre P, Viollet B, Foretz M, Marette A. Shum M, et al. Among authors: houde vp. J Biol Chem. 2019 Aug 9;294(32):12250-12260. doi: 10.1074/jbc.RA119.008488. Epub 2019 Jun 26. J Biol Chem. 2019. PMID: 31243102 Free PMC article.

10

Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatment.

Liu Y, Chewchuk S, Lavigne C, Brûlé S, Pilon G, Houde V, Xu A, Marette A, Sweeney G. Liu Y, et al. Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E657-64. doi: 10.1152/ajpendo.00186.2009. Epub 2009 Jun 16. Am J Physiol Endocrinol Metab. 2009. PMID: 19531641 Free article.

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