Hughes MC - Search Results

1

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1.

Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR. Smith BK, et al. Among authors: hughes mc. Diabetes. 2016 Nov;65(11):3352-3361. doi: 10.2337/db16-0564. Epub 2016 Aug 23. Diabetes. 2016. PMID: 27554471 Free PMC article.

2

An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo.

Williams CB, Hughes MC, Edgett BA, Scribbans TD, Simpson CA, Perry CG, Gurd BJ. Williams CB, et al. Among authors: hughes mc. PLoS One. 2014 Jul 14;9(7):e102406. doi: 10.1371/journal.pone.0102406. eCollection 2014. PLoS One. 2014. PMID: 25019209 Free PMC article. Clinical Trial.

3

Modelling in vivo creatine/phosphocreatine in vitro reveals divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic exercise.

Ydfors M, Hughes MC, Laham R, Schlattner U, Norrbom J, Perry CG. Ydfors M, et al. Among authors: hughes mc. J Physiol. 2016 Jun 1;594(11):3127-40. doi: 10.1113/JP271259. Epub 2016 Feb 4. J Physiol. 2016. PMID: 26631938 Free PMC article.

4

Mitochondrial Bioenergetics and Fiber Type Assessments in Microbiopsy vs. Bergstrom Percutaneous Sampling of Human Skeletal Muscle.

Hughes MC, Ramos SV, Turnbull PC, Nejatbakhsh A, Baechler BL, Tahmasebi H, Laham R, Gurd BJ, Quadrilatero J, Kane DA, Perry CG. Hughes MC, et al. Front Physiol. 2015 Dec 18;6:360. doi: 10.3389/fphys.2015.00360. eCollection 2015. Front Physiol. 2015. PMID: 26733870 Free PMC article.

5

SIRT3 gene expression but not SIRT3 subcellular localization is altered in response to fasting and exercise in human skeletal muscle.

Edgett BA, Hughes MC, Matusiak JB, Perry CG, Simpson CA, Gurd BJ. Edgett BA, et al. Among authors: hughes mc. Exp Physiol. 2016 Aug 1;101(8):1101-13. doi: 10.1113/EP085744. Exp Physiol. 2016. PMID: 27337034 Free article.

6

Decreased transcriptional corepressor p107 is associated with exercise-induced mitochondrial biogenesis in human skeletal muscle.

Bhattacharya D, Ydfors M, Hughes MC, Norrbom J, Perry CG, Scimè A. Bhattacharya D, et al. Among authors: hughes mc. Physiol Rep. 2017 Mar;5(5):e13155. doi: 10.14814/phy2.13155. Physiol Rep. 2017. PMID: 28270591 Free PMC article.

7

High-fat diet induces skeletal muscle oxidative stress in a fiber type-dependent manner in rats.

Pinho RA, Sepa-Kishi DM, Bikopoulos G, Wu MV, Uthayakumar A, Mohasses A, Hughes MC, Perry CGR, Ceddia RB. Pinho RA, et al. Among authors: hughes mc. Free Radic Biol Med. 2017 Sep;110:381-389. doi: 10.1016/j.freeradbiomed.2017.07.005. Epub 2017 Jul 6. Free Radic Biol Med. 2017. PMID: 28690197

8

Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes.

Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR. Monaco CMF, et al. Among authors: hughes mc. Diabetologia. 2018 Jun;61(6):1411-1423. doi: 10.1007/s00125-018-4602-6. Epub 2018 Apr 18. Diabetologia. 2018. PMID: 29666899

9

Altered skeletal muscle microtubule-mitochondrial VDAC2 binding is related to bioenergetic impairments after paclitaxel but not vinblastine chemotherapies.

Ramos SV, Hughes MC, Perry CGR. Ramos SV, et al. Among authors: hughes mc. Am J Physiol Cell Physiol. 2019 Mar 1;316(3):C449-C455. doi: 10.1152/ajpcell.00384.2018. Epub 2019 Jan 9. Am J Physiol Cell Physiol. 2019. PMID: 30624982 Free PMC article.

10

Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy.

Hughes MC, Ramos SV, Turnbull PC, Edgett BA, Huber JS, Polidovitch N, Schlattner U, Backx PH, Simpson JA, Perry CGR. Hughes MC, et al. J Physiol. 2020 Apr;598(7):1377-1392. doi: 10.1113/JP277306. Epub 2019 Feb 27. J Physiol. 2020. PMID: 30674086 Free article.

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