Lawrence MC - Search Results

1

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.

Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. Menting JG, et al. Among authors: lawrence mc. Nat Struct Mol Biol. 2016 Oct;23(10):916-920. doi: 10.1038/nsmb.3292. Epub 2016 Sep 12. Nat Struct Mol Biol. 2016. PMID: 27617429

2

Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase.

Lawrence MC, Barbosa JA, Smith BJ, Hall NE, Pilling PA, Ooi HC, Marcuccio SM. Lawrence MC, et al. J Mol Biol. 1997 Feb 21;266(2):381-99. doi: 10.1006/jmbi.1996.0769. J Mol Biol. 1997. PMID: 9047371

3

Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.

Barbosa JA, Smith BJ, DeGori R, Ooi HC, Marcuccio SM, Campi EM, Jackson WR, Brossmer R, Sommer M, Lawrence MC. Barbosa JA, et al. Among authors: lawrence mc. J Mol Biol. 2000 Oct 27;303(3):405-21. doi: 10.1006/jmbi.2000.4138. J Mol Biol. 2000. PMID: 11031117

4

The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion.

Chen L, Gorman JJ, McKimm-Breschkin J, Lawrence LJ, Tulloch PA, Smith BJ, Colman PM, Lawrence MC. Chen L, et al. Among authors: lawrence lj, lawrence mc. Structure. 2001 Mar 7;9(3):255-66. doi: 10.1016/s0969-2126(01)00581-0. Structure. 2001. PMID: 11286892 Free article.

5

Substrate-Assisted Catalysis in Sialic Acid Aldolase.

Smith BJ, Lawrence MC, Barbosa JA. Smith BJ, et al. Among authors: lawrence mc. J Org Chem. 1999 Feb 5;64(3):945-949. doi: 10.1021/jo981960v. J Org Chem. 1999. PMID: 11674166

6

Modelling the structure of the fusion protein from human respiratory syncytial virus.

Smith BJ, Lawrence MC, Colman PM. Smith BJ, et al. Among authors: lawrence mc. Protein Eng. 2002 May;15(5):365-71. doi: 10.1093/protein/15.5.365. Protein Eng. 2002. PMID: 12034856

7

Structure of the insulin receptor ectodomain reveals a folded-over conformation.

McKern NM, Lawrence MC, Streltsov VA, Lou MZ, Adams TE, Lovrecz GO, Elleman TC, Richards KM, Bentley JD, Pilling PA, Hoyne PA, Cartledge KA, Pham TM, Lewis JL, Sankovich SE, Stoichevska V, Da Silva E, Robinson CP, Frenkel MJ, Sparrow LG, Fernley RT, Epa VC, Ward CW. McKern NM, et al. Among authors: lawrence mc. Nature. 2006 Sep 14;443(7108):218-21. doi: 10.1038/nature05106. Epub 2006 Sep 6. Nature. 2006. PMID: 16957736

8

Insulin receptor structure and its implications for the IGF-1 receptor.

Lawrence MC, McKern NM, Ward CW. Lawrence MC, et al. Curr Opin Struct Biol. 2007 Dec;17(6):699-705. doi: 10.1016/j.sbi.2007.07.007. Epub 2007 Sep 11. Curr Opin Struct Biol. 2007. PMID: 17851071 Review.

9

N-linked glycans of the human insulin receptor and their distribution over the crystal structure.

Sparrow LG, Lawrence MC, Gorman JJ, Strike PM, Robinson CP, McKern NM, Ward CW. Sparrow LG, et al. Among authors: lawrence mc. Proteins. 2008 Apr;71(1):426-39. doi: 10.1002/prot.21768. Proteins. 2008. PMID: 17957771

10

Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.

Ward CW, Lawrence MC. Ward CW, et al. Among authors: lawrence mc. Bioessays. 2009 Apr;31(4):422-34. doi: 10.1002/bies.200800210. Bioessays. 2009. PMID: 19274663 Review.

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