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Page 1
Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.
Williams GS, Mistry B, Guillard S, Ulrichsen JC, Sandercock AM, Wang J, González-Muñoz A, Parmentier J, Black C, Soden J, Freeth J, Jovanović J, Leyland R, Al-Lamki RS, Leishman AJ, Rust SJ, Stewart R, Jermutus L, Bradley JR, Bedian V, Valge-Archer V, Minter R, Wilkinson RW. Williams GS, et al. Oncotarget. 2016 Oct 18;7(42):68278-68291. doi: 10.18632/oncotarget.11943. Oncotarget. 2016. PMID: 27626702 Free PMC article.
Phenotypic screening: the future of antibody discovery.
Gonzalez-Munoz AL, Minter RR, Rust SJ. Gonzalez-Munoz AL, et al. Drug Discov Today. 2016 Jan;21(1):150-156. doi: 10.1016/j.drudis.2015.09.014. Epub 2015 Oct 9. Drug Discov Today. 2016. PMID: 26440132 Review.
Tailored amino acid diversity for the evolution of antibody affinity.
González-Muñoz A, Bokma E, O'Shea D, Minton K, Strain M, Vousden K, Rossant C, Jermutus L, Minter R. González-Muñoz A, et al. MAbs. 2012 Nov-Dec;4(6):664-72. doi: 10.4161/mabs.21728. Epub 2012 Aug 27. MAbs. 2012. PMID: 22926024 Free PMC article.
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
MacGregor P, Gonzalez-Munoz AL, Jobe F, Taylor MC, Rust S, Sandercock AM, Macleod OJS, Van Bocxlaer K, Francisco AF, D'Hooge F, Tiberghien A, Barry CS, Howard P, Higgins MK, Vaughan TJ, Minter R, Carrington M. MacGregor P, et al. PLoS Negl Trop Dis. 2019 May 23;13(5):e0007373. doi: 10.1371/journal.pntd.0007373. eCollection 2019 May. PLoS Negl Trop Dis. 2019. PMID: 31120889 Free PMC article.
Very-high-energy particle acceleration powered by the jets of the microquasar SS 433.
Abeysekara AU, Albert A, Alfaro R, Alvarez C, Álvarez JD, Arceo R, Arteaga-Velázquez JC, Avila Rojas D, Ayala Solares HA, Belmont-Moreno E, BenZvi SY, Brisbois C, Caballero-Mora KS, Capistrán T, Carramiñana A, Casanova S, Castillo M, Cotti U, Cotzomi J, Coutiño de León S, De León C, De la Fuente E, Díaz-Vélez JC, Dichiara S, Dingus BL, DuVernois MA, Ellsworth RW, Engel K, Espinoza C, Fang K, Fleischhack H, Fraija N, Galván-Gámez A, García-González JA, Garfias F, González-Muñoz A, González MM, Goodman JA, Hampel-Arias Z, Harding JP, Hernandez S, Hinton J, Hona B, Hueyotl-Zahuantitla F, Hui CM, Hüntemeyer P, Iriarte A, Jardin-Blicq A, Joshi V, Kaufmann S, Kar P, Kunde GJ, Lauer RJ, Lee WH, León Vargas H, Li H, Linnemann JT, Longinotti AL, Luis-Raya G, López-Coto R, Malone K, Marinelli SS, Martinez O, Martinez-Castellanos I, Martínez-Castro J, Matthews JA, Miranda-Romagnoli P, Moreno E, Mostafá M, Nayerhoda A, Nellen L, Newbold M, Nisa MU, Noriega-Papaqui R, Pretz J, Pérez-Pérez EG, Ren Z, Rho CD, Rivière C, Rosa-González D, Rosenberg M, Ruiz-Velasco E, Salesa Greus F, Sandoval A, Schneider M, Schoorlemmer H, Seglar Arroyo M, Sinnis G, Smith AJ, Springer RW, Surajbali P, Taboada I, T… See abstract for full author list ➔ Abeysekara AU, et al. Nature. 2018 Oct;562(7725):82-85. doi: 10.1038/s41586-018-0565-5. Epub 2018 Oct 3. Nature. 2018. PMID: 30283106
Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.
Wicker LS, Moule CL, Fraser H, Penha-Goncalves C, Rainbow D, Garner VE, Chamberlain G, Hunter K, Howlett S, Clark J, Gonzalez-Munoz A, Cumiskey AM, Tiffen P, Howson J, Healy B, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB. Wicker LS, et al. Novartis Found Symp. 2005;267:57-65; discussion 65-75. doi: 10.1002/047002139x.ch6. Novartis Found Symp. 2005. PMID: 15999801
Publisher Correction: Very-high-energy particle acceleration powered by the jets of the microquasar SS 433.
Abeysekara AU, Albert A, Alfaro R, Alvarez C, Álvarez JD, Arceo R, Arteaga-Velázquez JC, Avila Rojas D, Ayala Solares HA, Belmont-Moreno E, BenZvi SY, Brisbois C, Caballero-Mora KS, Capistrán T, Carramiñana A, Casanova S, Castillo M, Cotti U, Cotzomi J, Coutiño de León S, De León C, De la Fuente E, Díaz-Vélez JC, Dichiara S, Dingus BL, DuVernois MA, Ellsworth RW, Engel K, Espinoza C, Fang K, Fleischhack H, Fraija N, Galván-Gámez A, García-González JA, Garfias F, González-Muñoz A, González MM, Goodman JA, Hampel-Arias Z, Harding JP, Hernandez S, Hinton J, Hona B, Hueyotl-Zahuantitla F, Hui CM, Hüntemeyer P, Iriarte A, Jardin-Blicq A, Joshi V, Kaufmann S, Kar P, Kunde GJ, Lauer RJ, Lee WH, León Vargas H, Li H, Linnemann JT, Longinotti AL, Luis-Raya G, López-Coto R, Malone K, Marinelli SS, Martinez O, Martinez-Castellanos I, Martínez-Castro J, Matthews JA, Miranda-Romagnoli P, Moreno E, Mostafá M, Nayerhoda A, Nellen L, Newbold M, Nisa MU, Noriega-Papaqui R, Pretz J, Pérez-Pérez EG, Ren Z, Rho CD, Rivière C, Rosa-González D, Rosenberg M, Ruiz-Velasco E, Salesa Greus F, Sandoval A, Schneider M, Schoorlemmer H, Seglar Arroyo M, Sinnis G, Smith AJ, Springer RW, Surajbali P, Taboada I, T… See abstract for full author list ➔ Abeysekara AU, et al. Nature. 2018 Dec;564(7736):E38. doi: 10.1038/s41586-018-0688-8. Nature. 2018. PMID: 30482938
Extended gamma-ray sources around pulsars constrain the origin of the positron flux at Earth.
Abeysekara AU, Albert A, Alfaro R, Alvarez C, Álvarez JD, Arceo R, Arteaga-Velázquez JC, Avila Rojas D, Ayala Solares HA, Barber AS, Bautista-Elivar N, Becerril A, Belmont-Moreno E, BenZvi SY, Berley D, Bernal A, Braun J, Brisbois C, Caballero-Mora KS, Capistrán T, Carramiñana A, Casanova S, Castillo M, Cotti U, Cotzomi J, Coutiño de León S, De León C, De la Fuente E, Dingus BL, DuVernois MA, Díaz-Vélez JC, Ellsworth RW, Engel K, Enríquez-Rivera O, Fiorino DW, Fraija N, García-González JA, Garfias F, Gerhardt M, González Muñoz A, González MM, Goodman JA, Hampel-Arias Z, Harding JP, Hernández S, Hernández-Almada A, Hinton J, Hona B, Hui CM, Hüntemeyer P, Iriarte A, Jardin-Blicq A, Joshi V, Kaufmann S, Kieda D, Lara A, Lauer RJ, Lee WH, Lennarz D, Vargas HL, Linnemann JT, Longinotti AL, Luis Raya G, Luna-García R, López-Coto R, Malone K, Marinelli SS, Martinez O, Martinez-Castellanos I, Martínez-Castro J, Martínez-Huerta H, Matthews JA, Miranda-Romagnoli P, Moreno E, Mostafá M, Nellen L, Newbold M, Nisa MU, Noriega-Papaqui R, Pelayo R, Pretz J, Pérez-Pérez EG, Ren Z, Rho CD, Rivière C, Rosa-González D, Rosenberg M, Ruiz-Velasco E, Salazar H, Salesa Greus F, Sandoval A, Schneider M, … See abstract for full author list ➔ Abeysekara AU, et al. Science. 2017 Nov 17;358(6365):911-914. doi: 10.1126/science.aan4880. Science. 2017. PMID: 29146808
Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.
Wicker LS, Chamberlain G, Hunter K, Rainbow D, Howlett S, Tiffen P, Clark J, Gonzalez-Munoz A, Cumiskey AM, Rosa RL, Howson JM, Smink LJ, Kingsnorth A, Lyons PA, Gregory S, Rogers J, Todd JA, Peterson LB. Wicker LS, et al. J Immunol. 2004 Jul 1;173(1):164-73. doi: 10.4049/jimmunol.173.1.164. J Immunol. 2004. PMID: 15210771
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