Baines AC - Search Results

1

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

Yuan X, Gavriilaki E, Thanassi JA, Yang G, Baines AC, Podos SD, Huang Y, Huang M, Brodsky RA. Yuan X, et al. Among authors: baines ac. Haematologica. 2017 Mar;102(3):466-475. doi: 10.3324/haematol.2016.153312. Epub 2016 Nov 3. Haematologica. 2017. PMID: 27810992 Free PMC article.

2

Complementopathies.

Baines AC, Brodsky RA. Baines AC, et al. Blood Rev. 2017 Jul;31(4):213-223. doi: 10.1016/j.blre.2017.02.003. Epub 2017 Feb 6. Blood Rev. 2017. PMID: 28215731 Free PMC article. Review.

3

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model.

Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. Yuan X, et al. Among authors: baines ac. PLoS One. 2017 Apr 25;12(4):e0174074. doi: 10.1371/journal.pone.0174074. eCollection 2017. PLoS One. 2017. PMID: 28441409 Free PMC article.

4

Germline mutations in the alternative pathway of complement predispose to HELLP syndrome.

Vaught AJ, Braunstein EM, Jasem J, Yuan X, Makhlin I, Eloundou S, Baines AC, Merrill SA, Chaturvedi S, Blakemore K, Sperati CJ, Brodsky RA. Vaught AJ, et al. Among authors: baines ac. JCI Insight. 2018 Mar 22;3(6):e99128. doi: 10.1172/jci.insight.99128. JCI Insight. 2018. PMID: 29563339 Free PMC article.

5

Disruption of the Sec24d gene results in early embryonic lethality in the mouse.

Baines AC, Adams EJ, Zhang B, Ginsburg D. Baines AC, et al. PLoS One. 2013 Apr 15;8(4):e61114. doi: 10.1371/journal.pone.0061114. Print 2013. PLoS One. 2013. PMID: 23596517 Free PMC article.

6

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.

Chen XW, Wang H, Bajaj K, Zhang P, Meng ZX, Ma D, Bai Y, Liu HH, Adams E, Baines A, Yu G, Sartor MA, Zhang B, Yi Z, Lin J, Young SG, Schekman R, Ginsburg D. Chen XW, et al. Elife. 2013 Apr 9;2:e00444. doi: 10.7554/eLife.00444. Elife. 2013. PMID: 23580231 Free PMC article.

7

Receptor-mediated protein transport in the early secretory pathway.

Baines AC, Zhang B. Baines AC, et al. Trends Biochem Sci. 2007 Aug;32(8):381-8. doi: 10.1016/j.tibs.2007.06.006. Epub 2007 Jul 6. Trends Biochem Sci. 2007. PMID: 17618120 Review.

8

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

Zhang B, Zheng C, Zhu M, Tao J, Vasievich MP, Baines A, Kim J, Schekman R, Kaufman RJ, Ginsburg D. Zhang B, et al. Blood. 2011 Sep 22;118(12):3384-91. doi: 10.1182/blood-2011-05-352815. Epub 2011 Jul 27. Blood. 2011. PMID: 21795745 Free PMC article.

9

Analysis of racial and ethnic disparities in multiple myeloma US FDA drug approval trials.

Kanapuru B, Fernandes LL, Fashoyin-Aje LA, Baines AC, Bhatnagar V, Ershler R, Gwise T, Kluetz P, Pazdur R, Pulte E, Shen YL, Gormley N. Kanapuru B, et al. Among authors: baines ac. Blood Adv. 2022 Mar 22;6(6):1684-1691. doi: 10.1182/bloodadvances.2021005482. Blood Adv. 2022. PMID: 35114691 Free PMC article.

10

Perspectives on Drug Development in Multiple Myeloma-Looking Forward to 2025.

Voorhees PM, Jakubowiak AJ, Kumar SK, Kanapuru B, Baines AC, Bhatnagar V, Ershler R, Theoret MR, Gormley NJ, Pazdur R. Voorhees PM, et al. Among authors: baines ac. Clin Cancer Res. 2022 Jan 1;28(1):23-26. doi: 10.1158/1078-0432.CCR-21-1069. Epub 2021 Jul 27. Clin Cancer Res. 2022. PMID: 34315721

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