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Page 1
Small molecule inhibitors of E. coli primase, a novel bacterial target.
Agarwal A, Louise-May S, Thanassi JA, Podos SD, Cheng J, Thoma C, Liu C, Wiles JA, Nelson DM, Phadke AS, Bradbury BJ, Deshpande MS, Pucci MJ. Agarwal A, et al. Among authors: thanassi ja. Bioorg Med Chem Lett. 2007 May 15;17(10):2807-10. doi: 10.1016/j.bmcl.2007.02.056. Epub 2007 Feb 25. Bioorg Med Chem Lett. 2007. PMID: 17350255
Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus.
Wiles JA, Song Y, Wang Q, Lucien E, Hashimoto A, Cheng J, Marlor CW, Ou Y, Podos SD, Thanassi JA, Thoma CL, Deshpande M, Pucci MJ, Bradbury BJ. Wiles JA, et al. Among authors: thanassi ja. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1277-81. doi: 10.1016/j.bmcl.2005.11.064. Epub 2005 Dec 7. Bioorg Med Chem Lett. 2006. PMID: 16337789
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells.
Wiles JA, Wang Q, Lucien E, Hashimoto A, Song Y, Cheng J, Marlor CW, Ou Y, Podos SD, Thanassi JA, Thoma CL, Deshpande M, Pucci MJ, Bradbury BJ. Wiles JA, et al. Among authors: thanassi ja. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1272-6. doi: 10.1016/j.bmcl.2005.11.065. Epub 2005 Dec 7. Bioorg Med Chem Lett. 2006. PMID: 16337791
Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.
Wang Q, Lucien E, Hashimoto A, Pais GC, Nelson DM, Song Y, Thanassi JA, Marlor CW, Thoma CL, Cheng J, Podos SD, Ou Y, Deshpande M, Pucci MJ, Buechter DD, Bradbury BJ, Wiles JA. Wang Q, et al. Among authors: thanassi ja. J Med Chem. 2007 Jan 25;50(2):199-210. doi: 10.1021/jm060844e. J Med Chem. 2007. PMID: 17228862
33 results