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Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.
Boross P, van Lent PL, Martin-Ramirez J, van der Kaa J, Mulder MH, Claassens JW, van den Berg WB, Arandhara VL, Verbeek JS. Boross P, et al. Among authors: verbeek js. J Immunol. 2008 Apr 1;180(7):5083-91. doi: 10.4049/jimmunol.180.7.5083. J Immunol. 2008. PMID: 18354234
Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis.
Bloemendaal FM, Levin AD, Wildenberg ME, Koelink PJ, McRae BL, Salfeld J, Lum J, van der Neut Kolfschoten M, Claassens JW, Visser R, Bentlage A, D'Haens GRAM, Verbeek JS, Vidarsson G, van den Brink GR. Bloemendaal FM, et al. Among authors: verbeek js. Gastroenterology. 2017 Nov;153(5):1351-1362.e4. doi: 10.1053/j.gastro.2017.07.021. Epub 2017 Jul 27. Gastroenterology. 2017. PMID: 28756234
FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model.
Sow HS, Benonisson H, Breukel C, Visser R, Verhagen OJHM, Bentlage AEH, Brouwers C, Claassens JWC, Linssen MM, Camps M, van Hall T, Ossendorp F, Fransen MF, Vidarsson G, Verbeek JS. Sow HS, et al. Among authors: verbeek js. Int J Cancer. 2019 Jan 15;144(2):345-354. doi: 10.1002/ijc.31899. Epub 2018 Nov 12. Int J Cancer. 2019. PMID: 30259976
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility.
Boross P, Arandhara VL, Martin-Ramirez J, Santiago-Raber ML, Carlucci F, Flierman R, van der Kaa J, Breukel C, Claassens JW, Camps M, Lubberts E, Salvatori D, Rastaldi MP, Ossendorp F, Daha MR, Cook HT, Izui S, Botto M, Verbeek JS. Boross P, et al. Among authors: verbeek js. J Immunol. 2011 Aug 1;187(3):1304-13. doi: 10.4049/jimmunol.1101194. Epub 2011 Jul 1. J Immunol. 2011. PMID: 21724994
FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis.
Yilmaz-Elis AS, Ramirez JM, Asmawidjaja P, van der Kaa J, Mus AM, Brem MD, Claassens JW, Breukel C, Brouwers C, Mangsbo SM, Boross P, Lubberts E, Verbeek JS. Yilmaz-Elis AS, et al. Among authors: verbeek js. J Immunol. 2014 Jun 15;192(12):5540-7. doi: 10.4049/jimmunol.1303272. Epub 2014 May 19. J Immunol. 2014. PMID: 24842758
134 results