Keating MJ - Search Results

1

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.

Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, Stone E. Cramer SL, et al. Among authors: keating mj. Nat Med. 2017 Jan;23(1):120-127. doi: 10.1038/nm.4232. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869804 Free PMC article.

2

Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells.

Iwasaki H, Huang P, Keating MJ, Plunkett W. Iwasaki H, et al. Among authors: keating mj. Blood. 1997 Jul 1;90(1):270-8. Blood. 1997. PMID: 9207462 Free article.

3

Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine.

Huang P, Sandoval A, Van Den Neste E, Keating MJ, Plunkett W. Huang P, et al. Among authors: keating mj. Leukemia. 2000 Aug;14(8):1405-13. doi: 10.1038/sj.leu.2401845. Leukemia. 2000. PMID: 10942236

4

Superoxide dismutase as a target for the selective killing of cancer cells.

Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W. Huang P, et al. Among authors: keating mj. Nature. 2000 Sep 21;407(6802):390-5. doi: 10.1038/35030140. Nature. 2000. PMID: 11014196

5

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents.

Zhou Y, Hileman EO, Plunkett W, Keating MJ, Huang P. Zhou Y, et al. Among authors: keating mj. Blood. 2003 May 15;101(10):4098-104. doi: 10.1182/blood-2002-08-2512. Epub 2003 Jan 16. Blood. 2003. PMID: 12531810 Free article.

6

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism.

Pelicano H, Feng L, Zhou Y, Carew JS, Hileman EO, Plunkett W, Keating MJ, Huang P. Pelicano H, et al. Among authors: keating mj. J Biol Chem. 2003 Sep 26;278(39):37832-9. doi: 10.1074/jbc.M301546200. Epub 2003 Jul 9. J Biol Chem. 2003. PMID: 12853461 Free article.

7

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

Carew JS, Zhou Y, Albitar M, Carew JD, Keating MJ, Huang P. Carew JS, et al. Among authors: keating mj. Leukemia. 2003 Aug;17(8):1437-47. doi: 10.1038/sj.leu.2403043. Leukemia. 2003. PMID: 12886229

8

Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity.

Hileman EO, Liu J, Albitar M, Keating MJ, Huang P. Hileman EO, et al. Among authors: keating mj. Cancer Chemother Pharmacol. 2004 Mar;53(3):209-19. doi: 10.1007/s00280-003-0726-5. Epub 2003 Nov 11. Cancer Chemother Pharmacol. 2004. PMID: 14610616

9

Increased mitochondrial biogenesis in primary leukemia cells: the role of endogenous nitric oxide and impact on sensitivity to fludarabine.

Carew JS, Nawrocki ST, Xu RH, Dunner K, McConkey DJ, Wierda WG, Keating MJ, Huang P. Carew JS, et al. Among authors: keating mj. Leukemia. 2004 Dec;18(12):1934-40. doi: 10.1038/sj.leu.2403545. Leukemia. 2004. PMID: 15483672

10

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

Xu RH, Pelicano H, Zhou Y, Carew JS, Feng L, Bhalla KN, Keating MJ, Huang P. Xu RH, et al. Among authors: keating mj. Cancer Res. 2005 Jan 15;65(2):613-21. Cancer Res. 2005. PMID: 15695406

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