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Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.
Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, Clare S, Jones SA, Godkin A, Jones GW, Humphreys IR. Clement M, et al. Among authors: abdul karim j. PLoS Pathog. 2016 Dec 7;12(12):e1006050. doi: 10.1371/journal.ppat.1006050. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27926930 Free PMC article.
The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis.
Stacey MA, Clare S, Clement M, Marsden M, Abdul-Karim J, Kane L, Harcourt K, Brandt C, Fielding CA, Smith SE, Wash RS, Brias SG, Stack G, Notley G, Cambridge EL, Isherwood C, Speak AO, Johnson Z, Ferlin W, Jones SA, Kellam P, Humphreys IR. Stacey MA, et al. Among authors: abdul karim j. J Clin Invest. 2017 Apr 3;127(4):1463-1474. doi: 10.1172/JCI84889. Epub 2017 Feb 27. J Clin Invest. 2017. PMID: 28240600 Free PMC article.
NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
Sowerby JM, Thomas DC, Clare S, Espéli M, Guerrero JA, Hoenderdos K, Harcourt K, Marsden M, Abdul-Karim J, Clement M, Antrobus R, Umrania Y, Barton PR, Flint SM, Juss JK, Condliffe AM, Lyons PA, Humphreys IR, Chilvers ER, Ouwehand WH, Dougan G, Smith KG. Sowerby JM, et al. Among authors: abdul karim j. J Clin Invest. 2017 Sep 1;127(9):3521-3526. doi: 10.1172/JCI91684. Epub 2017 Aug 7. J Clin Invest. 2017. PMID: 28783043 Free PMC article.