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Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.
van Eunen K, Simons SM, Gerding A, Bleeker A, den Besten G, Touw CM, Houten SM, Groen BK, Krab K, Reijngoud DJ, Bakker BM. van Eunen K, et al. Among authors: bleeker a. PLoS Comput Biol. 2013;9(8):e1003186. doi: 10.1371/journal.pcbi.1003186. Epub 2013 Aug 15. PLoS Comput Biol. 2013. PMID: 23966849 Free PMC article.
Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids.
Toonen EJ, Laskewitz AJ, van Dijk TH, Bleeker A, Grefhorst A, Schouten AE, Bastiaanssen EA, Ballak DB, Koenders MI, van Doorn C, van der Vleuten MA, van Lierop MJ, Groen AK, Dokter WH. Toonen EJ, et al. Among authors: bleeker a. PLoS One. 2014 Sep 2;9(9):e98684. doi: 10.1371/journal.pone.0098684. eCollection 2014. PLoS One. 2014. PMID: 25181348 Free PMC article.
Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1.
den Besten G, Gerding A, van Dijk TH, Ciapaite J, Bleeker A, van Eunen K, Havinga R, Groen AK, Reijngoud DJ, Bakker BM. den Besten G, et al. Among authors: bleeker a. PLoS One. 2015 Aug 20;10(8):e0136364. doi: 10.1371/journal.pone.0136364. eCollection 2015. PLoS One. 2015. PMID: 26292284 Free PMC article.
Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.
Lei Y, Hoogerland JA, Bloks VW, Bos T, Bleeker A, Wolters H, Wolters JC, Hijmans BS, van Dijk TH, Thomas R, van Weeghel M, Mithieux G, Houtkooper RH, de Bruin A, Rajas F, Kuipers F, Oosterveer MH. Lei Y, et al. Among authors: bleeker a. Hepatology. 2020 Nov;72(5):1638-1653. doi: 10.1002/hep.31198. Epub 2020 Oct 30. Hepatology. 2020. PMID: 32083759 Free PMC article.
Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.
Hoogerland JA, Peeks F, Hijmans BS, Wolters JC, Kooijman S, Bos T, Bleeker A, van Dijk TH, Wolters H, Gerding A, van Eunen K, Havinga R, Pronk ACM, Rensen PCN, Mithieux G, Rajas F, Kuipers F, Reijngoud DJ, Derks TGJ, Oosterveer MH. Hoogerland JA, et al. Among authors: bleeker a. J Inherit Metab Dis. 2021 Jul;44(4):879-892. doi: 10.1002/jimd.12380. Epub 2021 Apr 7. J Inherit Metab Dis. 2021. PMID: 33739445 Free PMC article.
53 results