Low YS - Search Results

1

Synergistic drug combinations from electronic health records and gene expression.

Low YS, Daugherty AC, Schroeder EA, Chen W, Seto T, Weber S, Lim M, Hastie T, Mathur M, Desai M, Farrington C, Radin AA, Sirota M, Kenkare P, Thompson CA, Yu PP, Gomez SL, Sledge GW Jr, Kurian AW, Shah NH. Low YS, et al. J Am Med Inform Assoc. 2017 May 1;24(3):565-576. doi: 10.1093/jamia/ocw161. J Am Med Inform Assoc. 2017. PMID: 27940607 Free PMC article.

2

Comparing high-dimensional confounder control methods for rapid cohort studies from electronic health records.

Low YS, Gallego B, Shah NH. Low YS, et al. J Comp Eff Res. 2016 Mar;5(2):179-92. doi: 10.2217/cer.15.53. Epub 2015 Dec 4. J Comp Eff Res. 2016. PMID: 26634383 Free PMC article.

3

Text mining for adverse drug events: the promise, challenges, and state of the art.

Harpaz R, Callahan A, Tamang S, Low Y, Odgers D, Finlayson S, Jung K, LePendu P, Shah NH. Harpaz R, et al. Drug Saf. 2014 Oct;37(10):777-90. doi: 10.1007/s40264-014-0218-z. Drug Saf. 2014. PMID: 25151493 Free PMC article.

4

Repurposing cAMP-modulating medications to promote β-cell replication.

Zhao Z, Low YS, Armstrong NA, Ryu JH, Sun SA, Arvanites AC, Hollister-Lock J, Shah NH, Weir GC, Annes JP. Zhao Z, et al. Among authors: low ys. Mol Endocrinol. 2014 Oct;28(10):1682-97. doi: 10.1210/me.2014-1120. Epub 2014 Aug 1. Mol Endocrinol. 2014. PMID: 25083741 Free PMC article.

5

Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome.

Low YS, Caster O, Bergvall T, Fourches D, Zang X, Norén GN, Rusyn I, Edwards R, Tropsha A. Low YS, et al. J Am Med Inform Assoc. 2016 Sep;23(5):968-78. doi: 10.1093/jamia/ocv127. Epub 2015 Oct 24. J Am Med Inform Assoc. 2016. PMID: 26499102 Free PMC article.

6

Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure-Activity Relationships.

Low YS, Alves VM, Fourches D, Sedykh A, Andrade CH, Muratov EN, Rusyn I, Tropsha A. Low YS, et al. J Chem Inf Model. 2018 Nov 26;58(11):2203-2213. doi: 10.1021/acs.jcim.8b00450. Epub 2018 Nov 9. J Chem Inf Model. 2018. PMID: 30376324 Free PMC article.

7

Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.

Low YS, Sedykh AY, Rusyn I, Tropsha A. Low YS, et al. Curr Top Med Chem. 2014;14(11):1356-64. doi: 10.2174/1568026614666140506121116. Curr Top Med Chem. 2014. PMID: 24805064 Free PMC article. Review.

8

Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches.

Low Y, Uehara T, Minowa Y, Yamada H, Ohno Y, Urushidani T, Sedykh A, Muratov E, Kuz'min V, Fourches D, Zhu H, Rusyn I, Tropsha A. Low Y, et al. Chem Res Toxicol. 2011 Aug 15;24(8):1251-62. doi: 10.1021/tx200148a. Epub 2011 Jul 21. Chem Res Toxicol. 2011. PMID: 21699217 Free PMC article.

9

Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data.

Rusyn I, Sedykh A, Low Y, Guyton KZ, Tropsha A. Rusyn I, et al. Toxicol Sci. 2012 May;127(1):1-9. doi: 10.1093/toxsci/kfs095. Epub 2012 Mar 2. Toxicol Sci. 2012. PMID: 22387746 Free PMC article.

10

Integrative chemical-biological read-across approach for chemical hazard classification.

Low Y, Sedykh A, Fourches D, Golbraikh A, Whelan M, Rusyn I, Tropsha A. Low Y, et al. Chem Res Toxicol. 2013 Aug 19;26(8):1199-208. doi: 10.1021/tx400110f. Epub 2013 Aug 5. Chem Res Toxicol. 2013. PMID: 23848138 Free PMC article.

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