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Targeting metastasis-initiating cells through the fatty acid receptor CD36.
Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA. Pascual G, et al. Nature. 2017 Jan 5;541(7635):41-45. doi: 10.1038/nature20791. Epub 2016 Dec 7. Nature. 2017. PMID: 27974793
The circadian molecular clock creates epidermal stem cell heterogeneity.
Janich P, Pascual G, Merlos-Suárez A, Batlle E, Ripperger J, Albrecht U, Cheng HY, Obrietan K, Di Croce L, Benitah SA. Janich P, et al. Among authors: pascual g. Nature. 2011 Nov 9;480(7376):209-14. doi: 10.1038/nature10649. Nature. 2011. PMID: 22080954
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.
Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. Ballaré C, et al. Among authors: pascual g. Nat Struct Mol Biol. 2012 Dec;19(12):1257-65. doi: 10.1038/nsmb.2434. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104054 Free PMC article.
A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos D, Kang TW, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H, Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ, Longerich T, Sansom OJ, Benitah SA, Zender L, Gil J. Acosta JC, et al. Among authors: pascual g. Nat Cell Biol. 2013 Aug;15(8):978-90. doi: 10.1038/ncb2784. Epub 2013 Jun 16. Nat Cell Biol. 2013. PMID: 23770676 Free PMC article.
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.
Ladanyi A, Mukherjee A, Kenny HA, Johnson A, Mitra AK, Sundaresan S, Nieman KM, Pascual G, Benitah SA, Montag A, Yamada SD, Abumrad NA, Lengyel E. Ladanyi A, et al. Among authors: pascual g. Oncogene. 2018 Apr;37(17):2285-2301. doi: 10.1038/s41388-017-0093-z. Epub 2018 Feb 5. Oncogene. 2018. PMID: 29398710 Free PMC article.
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma.
Lorenzo-Martín LF, Fernández-Parejo N, Menacho-Márquez M, Rodríguez-Fdez S, Robles-Valero J, Zumalave S, Fabbiano S, Pascual G, García-Pedrero JM, Abad A, García-Macías MC, González N, Lorenzano-Menna P, Pavón MA, González-Sarmiento R, Segrelles C, Paramio JM, Tubío JMC, Rodrigo JP, Benitah SA, Cuadrado M, Bustelo XR. Lorenzo-Martín LF, et al. Among authors: pascual g. Nat Commun. 2020 Sep 22;11(1):4788. doi: 10.1038/s41467-020-18524-3. Nat Commun. 2020. PMID: 32963234 Free PMC article.
198 results