Kursula I - Search Results

1

An Apicomplexan Actin-Binding Protein Serves as a Connector and Lipid Sensor to Coordinate Motility and Invasion.

Jacot D, Tosetti N, Pires I, Stock J, Graindorge A, Hung YF, Han H, Tewari R, Kursula I, Soldati-Favre D. Jacot D, et al. Among authors: kursula i. Cell Host Microbe. 2016 Dec 14;20(6):731-743. doi: 10.1016/j.chom.2016.10.020. Cell Host Microbe. 2016. PMID: 27978434 Free article.

2

Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family.

Myllykoski M, Raasakka A, Lehtimäki M, Han H, Kursula I, Kursula P. Myllykoski M, et al. Among authors: kursula i, kursula p. J Mol Biol. 2013 Nov 15;425(22):4307-22. doi: 10.1016/j.jmb.2013.06.012. Epub 2013 Jul 2. J Mol Biol. 2013. PMID: 23831225 Free PMC article.

3

Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress.

Salamun J, Kallio JP, Daher W, Soldati-Favre D, Kursula I. Salamun J, et al. Among authors: kursula i. FASEB J. 2014 Nov;28(11):4729-47. doi: 10.1096/fj.14-252569. Epub 2014 Aug 11. FASEB J. 2014. PMID: 25114175

4

Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies?

Kumpula EP, Kursula I. Kumpula EP, et al. Among authors: kursula i. Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):500-13. doi: 10.1107/S2053230X1500391X. Epub 2015 Apr 16. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25945702 Free PMC article. Review.

5

Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein.

Mueller C, Samoo A, Hammoudi PM, Klages N, Kallio JP, Kursula I, Soldati-Favre D. Mueller C, et al. Among authors: kursula i. J Cell Sci. 2016 Mar 1;129(5):1031-45. doi: 10.1242/jcs.177386. Epub 2016 Jan 14. J Cell Sci. 2016. PMID: 26769898

6

A unique profilin-actin interface is important for malaria parasite motility.

Moreau CA, Bhargav SP, Kumar H, Quadt KA, Piirainen H, Strauss L, Kehrer J, Streichfuss M, Spatz JP, Wade RC, Kursula I, Frischknecht F. Moreau CA, et al. Among authors: kursula i. PLoS Pathog. 2017 May 26;13(5):e1006412. doi: 10.1371/journal.ppat.1006412. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28552953 Free PMC article.

7

Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility.

Green JL, Wall RJ, Vahokoski J, Yusuf NA, Ridzuan MAM, Stanway RR, Stock J, Knuepfer E, Brady D, Martin SR, Howell SA, Pires IP, Moon RW, Molloy JE, Kursula I, Tewari R, Holder AA. Green JL, et al. Among authors: kursula i. J Biol Chem. 2017 Oct 27;292(43):17857-17875. doi: 10.1074/jbc.M117.802769. Epub 2017 Sep 11. J Biol Chem. 2017. PMID: 28893907 Free PMC article.

8

Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.

Pospich S, Kumpula EP, von der Ecken J, Vahokoski J, Kursula I, Raunser S. Pospich S, et al. Among authors: kursula i. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10636-10641. doi: 10.1073/pnas.1707506114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923924 Free PMC article.

9

Apicomplexan actin polymerization depends on nucleation.

Kumpula EP, Pires I, Lasiwa D, Piirainen H, Bergmann U, Vahokoski J, Kursula I. Kumpula EP, et al. Among authors: kursula i. Sci Rep. 2017 Sep 22;7(1):12137. doi: 10.1038/s41598-017-11330-w. Sci Rep. 2017. PMID: 28939886 Free PMC article.

10

A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress.

Pino P, Caldelari R, Mukherjee B, Vahokoski J, Klages N, Maco B, Collins CR, Blackman MJ, Kursula I, Heussler V, Brochet M, Soldati-Favre D. Pino P, et al. Among authors: kursula i. Science. 2017 Oct 27;358(6362):522-528. doi: 10.1126/science.aaf8675. Science. 2017. PMID: 29074775 Free PMC article.

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